Short-term results of laparoscopic anti-reflux surgery with the RefluxStop device in patients with gastro-esophageal reflux disease and ineffective esophageal motility.

Anti-reflux surgery Esophageal dysmotility Gastro-esophageal reflux disease Hiatal hernia Ineffective esophageal motility RefluxStop

Journal

Langenbeck's archives of surgery
ISSN: 1435-2451
Titre abrégé: Langenbecks Arch Surg
Pays: Germany
ID NLM: 9808285

Informations de publication

Date de publication:
29 Feb 2024
Historique:
received: 11 09 2023
accepted: 17 02 2024
medline: 29 2 2024
pubmed: 29 2 2024
entrez: 28 2 2024
Statut: epublish

Résumé

In gastro-esophageal reflux disease (GERD) requiring surgical treatment, concomitant ineffective esophageal motility (IEM) is a decisive factor in surgical planning, due to concern regarding dysphagia. Anti-reflux surgery with the RefluxStop device is a promising technique. We assessed initial feasibility and clinical outcomes of RefluxStop surgery in patients with GERD and IEM. Retrospective analysis of patients with GERD, hiatal hernia (HH), and IEM, who underwent surgery with RefluxStop at our institution and achieved 12-month follow-up. Technique feasibility was assessed, in addition to symptom resolution (GERD-HRQL questionnaire), adverse events, HH recurrence, dysphagia, and patient satisfaction. Placement of the device was confirmed by video fluoroscopy on postoperative day 1, and at 3 and 12 months. Between June 2020 and November 2022, 20 patients with IEM underwent surgery with RefluxStop and completed 12-month follow-up. All patients reported typical symptoms of GERD, and 12 had preoperative dysphagia. The median HH length was 4.5 cm (IQR, 3.75-5). The median operating time was 59.5 min (IQR, 50.25-64) with no implant-related intra- or postoperative complications. No HH recurrence was observed. One patient reported persistent left-sided thoracic pain at 11 months post-surgery, which required diagnostic laparoscopy and adhesiolysis. Three patients reported severe postoperative dysphagia: balloon dilatation was performed towards resolution. The mean GERD-HRQL scores improved (from 40.7 at baseline to 4.8 at 3 months and 5.7 at 12 months (p <0.001)). RefluxStop surgery was feasible and offered effective treatment for this group of patients with GERD and IEM. All patients had complete resolution or significant improvement of GERD symptoms, and 90% of them were satisfied with their quality of life 1 year after surgery.

Identifiants

pubmed: 38418718
doi: 10.1007/s00423-024-03264-5
pii: 10.1007/s00423-024-03264-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

78

Informations de copyright

© 2024. The Author(s).

Références

Ganz RA (2016) A review of new surgical and endoscopic therapies for gastroesophageal reflux disease. Gastroenterol Hepatol (NY) 12(7):424–31
Hillman L, Yadlapati R, Thuluvath AJ, Berendsen MA, Pandolfino JE (2017) A review of medical therapy for proton pump inhibitor nonresponsive gastroesophageal reflux disease. Dis Esophagus 30(9):1–15. https://doi.org/10.1093/dote/dox055
doi: 10.1093/dote/dox055 pubmed: 28859358 pmcid: 5789775
Bjelović M, Harsányi L, Altorjay Á, Kincses Z, Forsell P (2020) Non-active implantable device treating acid reflux with a new dynamic treatment approach: 1-year results : RefluxStop™ device; a new method in acid reflux surgery obtaining CE mark. BMC Surg 20(1):159. https://doi.org/10.1186/s12893-020-00794-9
doi: 10.1186/s12893-020-00794-9 pubmed: 32689979 pmcid: 7370422
Gyawali CP, Sifrim D, Carlson DA, Hawn M, Katzka DA, Pandolfino JE et al (2019) Ineffective esophageal motility: concepts, future directions, and conclusions from the Stanford 2018 symposium. Neurogastroenterol Motil 31(9):e13584. https://doi.org/10.1111/nmo.13584
doi: 10.1111/nmo.13584 pubmed: 30974032 pmcid: 9380027
Alani M, Al-Jashaami L, Mills M, Guha S, Ratuapli SK (2018) Prevalence of esophageal motility disorders in an open access hybrid “academic - community setting” patient population: 325. Off J Am College of Gastroenterol|ACG;113:S180-S1
Abdel Jalil AA, Castell DO (2016) Ineffective esophageal motility (IEM): the Old-New Frontier in Esophagology. Curr Gastroenterol Rep 18(1):1. https://doi.org/10.1007/s11894-015-0472-y
doi: 10.1007/s11894-015-0472-y pubmed: 26685862
Smith CD, DeVault KR, Buchanan M (2014) Introduction of mechanical sphincter augmentation for gastroesophageal reflux disease into practice: early clinical outcomes and keys to successful adoption. J Am Coll Surg 218(4):776–81. https://doi.org/10.1016/j.jamcollsurg.2013.12.034
doi: 10.1016/j.jamcollsurg.2013.12.034 pubmed: 24529809
Furay E, Doggett S, Buckley III FP (2023) Criteria of patient selection for magnetic sphincter augmentation. Dis Esophagus 36(Supplement_1) https://doi.org/10.1093/dote/doac115
Allen JE, White C, Leonard R, Belafsky PC (2012) Comparison of esophageal screen findings on videofluoroscopy with full esophagram results. Head Neck. 34(2):264–9. https://doi.org/10.1002/hed.21727
doi: 10.1002/hed.21727 pubmed: 21472881
Lundell LR, Dent J, Bennett JR, Blum AL, Armstrong D, Galmiche JP et al (1999) Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut 45(2):172–80. https://doi.org/10.1136/gut.45.2.172
doi: 10.1136/gut.45.2.172 pubmed: 10403727 pmcid: 1727604
Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–13. https://doi.org/10.1097/01.sla.0000133083.54934.ae
doi: 10.1097/01.sla.0000133083.54934.ae pubmed: 15273542 pmcid: 1360123
Nabi Z, Reddy DN (2016) Endoscopic management of gastroesophageal reflux disease: revisited. Clin Endosc 49(5):408–16. https://doi.org/10.5946/ce.2016.133
doi: 10.5946/ce.2016.133 pubmed: 27744659 pmcid: 5066398
Zornig C, Strate U, Fibbe C, Emmermann A, Layer P (2002) Nissen vs Toupet laparoscopic fundoplication. Surg Endosc 16(5):758–66. https://doi.org/10.1007/s00464-001-9092-8
doi: 10.1007/s00464-001-9092-8 pubmed: 11997817
Raue W, Ordemann J, Jacobi CA, Menenakos C, Buchholz A, Hartmann J (2011) Nissen versus Dor fundoplication for treatment of gastroesophageal reflux disease: a blinded randomized clinical trial. Dig Surg 28(1):80–6. https://doi.org/10.1159/000323630
doi: 10.1159/000323630 pubmed: 21293136
Addo A, George P, Zahiri HR, Park A (2021) Patients with ineffective esophageal motility benefit from laparoscopic antireflux surgery. Surg Endosc 35(8):4459–68. https://doi.org/10.1007/s00464-020-07951-4
doi: 10.1007/s00464-020-07951-4 pubmed: 32959180
Nguyen NT, Thosani NC, Canto MI, Chang K, Lipham J, Abu Dayyeh B et al (2022) The American Foregut Society white paper on the endoscopic classification of esophagogastric junction integrity. Foregut: J Am Foregut Soc 2(4):339–48. https://doi.org/10.1177/26345161221126961
doi: 10.1177/26345161221126961
Schwameis K, Zehetner J, Rona K, Crookes P, Bildzukewicz N, Oh DS et al (2017) Post-Nissen dysphagia and bloating syndrome: outcomes after conversion to Toupet fundoplication. J Gastrointest Surg. 21(3):441–5. https://doi.org/10.1007/s11605-016-3320-y
doi: 10.1007/s11605-016-3320-y pubmed: 27834011
Yadlapati R, Kahrilas PJ, Fox MR, Bredenoord AJ, Prakash Gyawali C, Roman S et al (2021) Esophageal motility disorders on high-resolution manometry Chicago classification version 40(©). Neurogastroenterol Motil 33(1):e14058 https://doi.org/10.1111/nmo.14058
Richter JE (2021) Chicago Classification version 40 and its impact on current clinical practice. Gastroenterol Hepatol (NY) 17(10):468-75
Patel DA, Yadlapati R, Vaezi MF (2022) Esophageal motility disorders: current approach to diagnostics and therapeutics. Gastroenterology 162(6):1617–34. https://doi.org/10.1053/j.gastro.2021.12.289
doi: 10.1053/j.gastro.2021.12.289 pubmed: 35227779
Wilkinson JM, Halland M (2020) Esophageal motility disorders. Am Fam Physician. 102(5):291–6
pubmed: 32866357

Auteurs

Yannick Fringeli (Y)

Department of Visceral Surgery, Hirslanden Clinic Beau-Site, 3013, Bern, Switzerland.

Ioannis Linas (I)

Department of Gastroenterology, Hirslanden Clinic Beau-Site, 3013, Bern, Switzerland.

Ulf Kessler (U)

Department of Visceral Surgery, Hirslanden Clinic Beau-Site, 3013, Bern, Switzerland.

Joerg Zehetner (J)

Department of Visceral Surgery, Hirslanden Clinic Beau-Site, 3013, Bern, Switzerland. joerg.zehetner@hirslanden.ch.

Classifications MeSH