Impact of thrombosis location on walking capacity: a cohort study of patients with acute deep vein thrombosis.
deep vein thrombosis
exercise test
mobility limitation
quality of life
venous thromboembolism
Journal
Research and practice in thrombosis and haemostasis
ISSN: 2475-0379
Titre abrégé: Res Pract Thromb Haemost
Pays: United States
ID NLM: 101703775
Informations de publication
Date de publication:
Jan 2024
Jan 2024
Historique:
received:
27
10
2023
revised:
28
12
2023
accepted:
16
01
2024
medline:
29
2
2024
pubmed:
29
2
2024
entrez:
29
2
2024
Statut:
epublish
Résumé
Data on walking impairment during the acute phase of deep vein thrombosis (DVT) are limited. This study aimed to assess the degree of walking impairment in patients with acute DVT, with a particular focus on the relation to the DVT's anatomical location. Patients with sonographically confirmed DVT were eligible for inclusion in this cohort study. Pain-free walking distance (PWD) and maximum walking distance (MWD) were determined using standardized treadmill ergometer tests and analyzed in relation to DVT location. The impact of previous DVT on walking capacity was evaluated in an exploratory analysis. The study included 64 patients (31% women; median age, 55 years). The median (IQR) time from diagnosis to exercise test was 3 (1-5) days. Patients with suprainguinal DVT demonstrated significantly shorter median (IQR) MWD than those with infrainguinal DVT (130 (61-202) m vs 565 (128-750) m; Suprainguinal DVT was linked to a more pronounced walking impairment compared with infrainguinal DVT. Limited walking capacity was associated with a reduced quality of life.
Sections du résumé
Background
UNASSIGNED
Data on walking impairment during the acute phase of deep vein thrombosis (DVT) are limited.
Objectives
UNASSIGNED
This study aimed to assess the degree of walking impairment in patients with acute DVT, with a particular focus on the relation to the DVT's anatomical location.
Methods
UNASSIGNED
Patients with sonographically confirmed DVT were eligible for inclusion in this cohort study. Pain-free walking distance (PWD) and maximum walking distance (MWD) were determined using standardized treadmill ergometer tests and analyzed in relation to DVT location. The impact of previous DVT on walking capacity was evaluated in an exploratory analysis.
Results
UNASSIGNED
The study included 64 patients (31% women; median age, 55 years). The median (IQR) time from diagnosis to exercise test was 3 (1-5) days. Patients with suprainguinal DVT demonstrated significantly shorter median (IQR) MWD than those with infrainguinal DVT (130 (61-202) m vs 565 (128-750) m;
Conclusion
UNASSIGNED
Suprainguinal DVT was linked to a more pronounced walking impairment compared with infrainguinal DVT. Limited walking capacity was associated with a reduced quality of life.
Identifiants
pubmed: 38419653
doi: 10.1016/j.rpth.2024.102324
pii: S2475-0379(24)00011-6
pmc: PMC10899038
doi:
Types de publication
Journal Article
Langues
eng
Pagination
102324Informations de copyright
© 2024 The Author(s).