Physiological cell bioprinting density in human bone-derived cell-laden scaffolds enhances matrix mineralization rate and stiffness under dynamic loading.

3D bioprinting cell density cell-laden scaffold dynamic culture time-lapsed micro-CT

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2024
Historique:
received: 09 10 2023
accepted: 30 01 2024
medline: 29 2 2024
pubmed: 29 2 2024
entrez: 29 2 2024
Statut: epublish

Résumé

Human organotypic bone models are an emerging technology that replicate bone physiology and mechanobiology for comprehensive

Identifiants

pubmed: 38419730
doi: 10.3389/fbioe.2024.1310289
pii: 1310289
pmc: PMC10900528
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1310289

Informations de copyright

Copyright © 2024 de Leeuw, Graf, Lim, Zhang, Schädli, Peterhans, Rohrbach, Giunta, Rüger, Rubert and Müller.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Auteurs

Anke M de Leeuw (AM)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Reto Graf (R)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Pei Jin Lim (PJ)

Connective Tissue Unit, Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.

Jianhua Zhang (J)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Gian Nutal Schädli (GN)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Sheila Peterhans (S)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Marianne Rohrbach (M)

Connective Tissue Unit, Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.

Cecilia Giunta (C)

Connective Tissue Unit, Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.

Matthias Rüger (M)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.
Department of Pediatric Orthopaedics and Traumatology, University Children's Hospital Zurich, Zurich, Switzerland.

Marina Rubert (M)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Ralph Müller (R)

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Classifications MeSH