828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser.
Journal
Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630
Informations de publication
Date de publication:
01 Dec 2023
01 Dec 2023
Historique:
received:
31
08
2023
revised:
08
11
2023
accepted:
16
11
2023
medline:
29
2
2024
pubmed:
29
2
2024
entrez:
29
2
2024
Statut:
epublish
Résumé
This paper presents a Fourier domain mode locked (FDML) laser centered around 840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sensitivity roll-off are achieved. Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently high sensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during optical coherence tomography (OCT) examination. The developed FDML laser enables acquisition rates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailed information on the FDML implementation, its challenging design tasks, and OCT images obtained with the laser are presented in this paper.
Identifiants
pubmed: 38420314
doi: 10.1364/BOE.504302
pii: 504302
pmc: PMC10898573
doi:
Types de publication
Journal Article
Langues
eng
Pagination
6493-6508Informations de copyright
© 2023 Optica Publishing Group.
Déclaration de conflit d'intérêts
T. Pfeiffer: University of Lübeck (P), Optores GmbH (E); A. Mlynek: Optores GmbH (E); W. Wieser: Ludwig Maximilian University of Munich (P), Optores GmbH (I, E); A. Chamorovskiy: Superlum Ltd. (E); A. Bradu: University of Kent (P); A. Podoleanu: University of Kent (P); R. Huber: University of Lübeck (P), Ludwig Maximilian University of Munich (P), Optores GmbH (I, P, R), Optovue Inc. (I, R), Abott (I, R).