Vanillin derivatives as antiamnesic agents in scopolamine-induced memory impairment in mice.

Acetylcholinesterase Antiamnesic Antioxidant Butyrylcholinesterase DPPH Schiff bases Vanillin

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
29 Feb 2024
Historique:
received: 24 02 2023
revised: 23 01 2024
accepted: 16 02 2024
medline: 29 2 2024
pubmed: 29 2 2024
entrez: 29 2 2024
Statut: epublish

Résumé

Amnesia is a major health problem prevalent in almost every part of the world specifically in old age peoples. Vanillin analogues have played an important role in the field medicines. Some of them have been documented to be promising inhibitors of cholinesterases and could therefore, be used as antidepressant, anti-Alzheimer and as neuroprotective drugs. In this connection, the present study was designed to synthesize new vanillin analogues (

Identifiants

pubmed: 38420420
doi: 10.1016/j.heliyon.2024.e26657
pii: S2405-8440(24)02688-4
pmc: PMC10901097
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e26657

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Qamar Gul (Q)

Department of Pharmacy, University of Malakand, Chakdara Dir Lower, KPK, Pakistan.

Nasiara Karim (N)

Department of Pharmacy, University of Peshawar, Peshawar, KPK, Pakistan.

Mohammad Shoaib (M)

Department of Pharmacy, University of Malakand, Chakdara Dir Lower, KPK, Pakistan.

Muhammad Zahoor (M)

Department of Biochemistry, University of Malakand Chakdara Dir Lower, KPK, Pakistan.

Mehboob Ur Rahman (MU)

Department of Pharmacy, University of Malakand, Chakdara Dir Lower, KPK, Pakistan.

Hayat Bilal (H)

Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, KPK, Pakistan.

Riaz Ullah (R)

Medicinal Aromatic and Poisonous Plants Research Center College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Amal Alotaibi (A)

Department of Basic Science, College of Medicine, Princess Nourah Bint Abdulrahman University, 11671, Riyadh, Saudi Arabia.

Classifications MeSH