Effect of stapes demineralisation on the development of cochlear otosclerosis.
cochlear otosclerosis
otosclerotic lesions
scanning electron microscope
stapes demineralisation
stapes microstructure
Journal
Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale
ISSN: 1827-675X
Titre abrégé: Acta Otorhinolaryngol Ital
Pays: Italy
ID NLM: 8213019
Informations de publication
Date de publication:
29 Feb 2024
29 Feb 2024
Historique:
received:
24
09
2022
accepted:
16
10
2023
medline:
29
2
2024
pubmed:
29
2
2024
entrez:
29
2
2024
Statut:
aheadofprint
Résumé
The involvement of the inner ear in otosclerosis may lead to the development of cochlear otosclerosis. The aim of this study was to analyse changes in the chemical composition and microstructure of the stapes in the course of otosclerosis compared to healthy stapes. This analysis included 31 patients with otosclerosis and 9 patients without otosclerosis. Microanalytical and diffraction techniques were used to assess the elemental distribution and orientation topography of the stapes. The concentration of Ca Bone remodelling is most significant at the closest location to typical otosclerotic lesions with hydroxyapatite porosity and scale-like bone formation according to scanning electron microscopy. There is a relationship between the disturbance of calcium metabolism and the development of clinical symptoms of cochlear otosclerosis.
Identifiants
pubmed: 38420840
doi: 10.14639/0392-100X-N2389
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy.