Acoustics and aerodynamic effects following glottal and infraglottal medialization in an excised larynx model.

Implant location Intraglottal flow Medialization laryngoplasty Unilateral vocal fold paralysis Vocal efficiency

Journal

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937

Informations de publication

Date de publication:
May 2024
Historique:
received: 30 10 2023
accepted: 30 01 2024
medline: 18 4 2024
pubmed: 29 2 2024
entrez: 29 2 2024
Statut: ppublish

Résumé

This study aimed to investigate the impact of the implant's vertical location during Type 1 Thyroplasty (T1T) on acoustics and glottal aerodynamics using excised canine larynx model, providing insights into the optimal technique for treating unilateral vocal fold paralysis (UVFP). Measurements were conducted in six excised canine larynges using Silastic implants. Two implant locations, glottal and infraglottal, were tested for each larynx at low and high subglottal pressure levels. Acoustic and intraglottal flow velocity field measurements were taken to assess vocal efficiency (VE), cepstral peak prominence (CPP), and the development of intraglottal vortices. The results indicated that the implant's vertical location significantly influenced vocal efficiency (p = 0.045), with the infraglottal implant generally yielding higher VE values. The effect on CPP was not statistically significant (p = 0.234). Intraglottal velocity field measurements demonstrated larger glottal divergence angles and stronger vortices with the infraglottal implant. The findings suggest that medializing the paralyzed fold at the infraglottal level rather than the glottal level can lead to improved vocal efficiency. The observed larger divergence angles and stronger intraglottal vortices with infraglottal medialization may enhance voice outcomes in UVFP patients. These findings have important implications for optimizing T1T procedures and improving voice quality in individuals with UVFP. Further research is warranted to validate these results in clinical settings.

Identifiants

pubmed: 38421393
doi: 10.1007/s00405-024-08519-x
pii: 10.1007/s00405-024-08519-x
pmc: PMC11024032
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2523-2529

Subventions

Organisme : NIDCD NIH HHS
ID : R01 DC009435
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01DC009435
Pays : United States

Informations de copyright

© 2024. The Author(s).

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Auteurs

Liran Oren (L)

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA. liran.oren@uc.edu.

Alexandra Maddox (A)

Department of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, OH, USA.

Charles Farbos de Luzan (C)

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.

Changchun Xie (C)

Department of Environmental and Public Health Sciences, University of Cincinnati, Cincinnati, OH, USA.

Rebecca Howell (R)

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.

Gregory Dion (G)

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.

Ephraim Gutmark (E)

Department of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, OH, USA.

Sid Khosla (S)

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.

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