Overview of Neutrophilic Biology, Pathophysiology, and Classification of Neutrophilic Dermatoses.

Autoinflammation Myeloid neoplasm Neutrophilic dermatoses neutrophils

Journal

Dermatologic clinics
ISSN: 1558-0520
Titre abrégé: Dermatol Clin
Pays: United States
ID NLM: 8300886

Informations de publication

Date de publication:
Apr 2024
Historique:
medline: 1 3 2024
pubmed: 1 3 2024
entrez: 29 2 2024
Statut: ppublish

Résumé

Neutrophilic dermatoses are a group of inflammatory skin conditions characterized by a neutrophilic infiltrate on histopathology with no evidence of infection. These conditions present with a wide range of clinical manifestations, including pustules, bullae, abscesses, papules, nodules, plaques, and ulcers. The classification of neutrophilic dermatoses is based on the localization of neutrophils in the skin. The pathogenic mechanisms of neutrophilic dermatoses involve autoinflammation, neutrophilic dysfunction, clonal somatic mutation and differentiation of the myeloid precursors as encountered in myeloid neoplasm.

Identifiants

pubmed: 38423677
pii: S0733-8635(23)00072-4
doi: 10.1016/j.det.2023.08.002
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

147-156

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Jérémie Delaleu (J)

Dermatology Department, Saint Louis Hospital, APHP Nord Université Paris Cité and INSERM u976 "Human Immunology, Pathophysiology and Immunotherapy", Paris, France.

Jean-David Bouaziz (JD)

Dermatology Department, Saint Louis Hospital, APHP Nord Université Paris Cité and INSERM u976 "Human Immunology, Pathophysiology and Immunotherapy", Paris, France. Electronic address: jean-david.bouaziz@aphp.fr.

Classifications MeSH