Retigabine and gabapentin restore channel function and neuronal firing in a cellular model of an epilepsy-associated dominant-negative KCNQ5 variant.
Genetic generalized epilepsy
Genetics
K(V)7 channel activator
Neuronal culture
Patch-clamp
ion channel
Journal
Neuropharmacology
ISSN: 1873-7064
Titre abrégé: Neuropharmacology
Pays: England
ID NLM: 0236217
Informations de publication
Date de publication:
28 Feb 2024
28 Feb 2024
Historique:
received:
13
09
2023
revised:
19
01
2024
accepted:
26
02
2024
medline:
2
3
2024
pubmed:
2
3
2024
entrez:
1
3
2024
Statut:
aheadofprint
Résumé
KCNQ5 encodes the voltage-gated potassium channel K
Identifiants
pubmed: 38428481
pii: S0028-3908(24)00059-5
doi: 10.1016/j.neuropharm.2024.109892
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109892Informations de copyright
Copyright © 2024. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare no conflict of interest.