Risk factors for Echinococcus multilocularis intestinal infections in owned domestic dogs in a North American metropolis (Calgary, Alberta).
Echinococcus multilocularis
Alveolar echinococcosis
Canada
Cross-sectional study
Domestic dogs
Intestinal echinococcosis
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
01 Mar 2024
01 Mar 2024
Historique:
received:
08
08
2023
accepted:
24
02
2024
medline:
2
3
2024
pubmed:
2
3
2024
entrez:
1
3
2024
Statut:
epublish
Résumé
Human alveolar echinococcosis is increasingly documented in Alberta, Canada. Its causative agent, Echinococcus multilocularis (Em), can be transmitted to humans by infected dogs. We assessed the prevalence and associated risk factors for Em infections in domestic dogs in Calgary, Alberta, Canada. In this cross-sectional study that coupled collection and assessment of dog feces with a survey on potential risk factors, 13 of 696 (Bayesian true prevalence, 2.4%; 95% CrI: 1.3-4.0%) individual dogs' feces collected during August and September 2012 were qPCR positive for Em. Sequencing two of these cases indicated that both were from the same Em European strain responsible for human infections in Alberta. Likelihood of intestinal Em was 5.6-times higher in hounds than other breeds, 4.6-times higher in dogs leashed at dog parks than those allowed off-leash, 3.1-times higher in dogs often kept in the backyard during spring and summer months than those rarely in the yard, and 3.3-times higher in dogs living in neighbourhoods bordering Bowmont park than those in other areas of Calgary. This situation warrants surveillance of dog infections as a preventative measure to reduce infections in North America.
Identifiants
pubmed: 38429417
doi: 10.1038/s41598-024-55515-6
pii: 10.1038/s41598-024-55515-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5066Subventions
Organisme : National Recovery and Resilience Plan (NRRP), Project title "National Biodiversity Future Center -NBFC"
ID : CUP J33C22001190001
Organisme : Elanco Canada Limited
ID : 10017067
Organisme : Mathematics of Information Technology and Complex Systems (MITACS) Accelerate, Canada
ID : 10018836
Organisme : Alberta Conservation Association, Canada
ID : 030-00-90-269
Informations de copyright
© 2024. The Author(s).
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