Human orf virus (family Poxviridae) infection following a lamb bite in Hungary.


Journal

Archives of virology
ISSN: 1432-8798
Titre abrégé: Arch Virol
Pays: Austria
ID NLM: 7506870

Informations de publication

Date de publication:
02 Mar 2024
Historique:
received: 14 12 2023
accepted: 23 01 2024
medline: 4 3 2024
pubmed: 2 3 2024
entrez: 2 3 2024
Statut: epublish

Résumé

Human orf disease (called ecthyma contagiosum or contagious/infectious pustular dermatitis in animals) was confirmed on the fingers of both hands of a 24-year-old female, after feeding diseased lambs with a nursing bottle in April 2023. In addition to skin symptoms, she had low-grade fever (37.6°C) and swollen lymph nodes in both axilla. The presence of orf virus (genus Parapoxvirus, family Poxviridae) was confirmed, and this strain, Baja/2023/HUN (OR372161-OR372163), was found to have > 98% nucleotide sequence identity to sheep-origin orf viruses in four tested genome regions (ORF011/B2L, ORF019, ORF020/VIR, and ORF056). This is the first report of a human case of infection with the neglected zoonotic orf virus in Hungary.

Identifiants

pubmed: 38430421
doi: 10.1007/s00705-024-06002-w
pii: 10.1007/s00705-024-06002-w
pmc: PMC10908620
doi:

Substances chimiques

DNA, Viral 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

59

Informations de copyright

© 2024. The Author(s).

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Auteurs

Csongor Németh (C)

Department of Dermatology, Venereology and Oncodermatology, Medical School, University of Pécs, Pécs, Hungary.

Ákos Boros (Á)

Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12, H-7624, Pécs, Hungary.

Endre Mészáros (E)

Szent Rókus Hospital, Baja, Hungary.

Csaba Gyömörei (C)

Department of Pathology, Medical School, University of Pécs, Pécs, Hungary.

Ervin Albert (E)

Department of Pathology, University of Veterinary Medicine, Budapest, Hungary.

Péter Pankovics (P)

Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12, H-7624, Pécs, Hungary.

Gábor Reuter (G)

Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12, H-7624, Pécs, Hungary. reuter.gabor@gmail.com.

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