Metabolomics of male infertility.

Humans Male Infertility, Male / diagnosis Biomarkers / metabolism Metabolomics Precision Medicine
Diagnosis Infertility Male reproductive function Metabolomics Therapy

Journal

Clinica chimica acta; international journal of clinical chemistry
ISSN: 1873-3492
Titre abrégé: Clin Chim Acta
Pays: Netherlands
ID NLM: 1302422

Informations de publication

Date de publication:
15 Mar 2024
Historique:
received: 16 12 2023
revised: 26 02 2024
accepted: 27 02 2024
medline: 18 3 2024
pubmed: 3 3 2024
entrez: 2 3 2024
Statut: ppublish

Résumé

This review explores the use of metabolomics in male infertility. Metabolomics, an evolving omics technology that targets the products of cellular metabolism, is valuable for elucidating underlying pathophysiology of many disorders including male infertility. The identification of reliable biomarkers is essential for accurate diagnosis and for developing precision therapeutics for those afflicted by reproductive dysfunction. Unfortunately, despite significant progress to date, the intricate relationships between these metabolic pathways and male infertility remain elusive. It is clear, however, that additional research is required to more fully characterize the role of metabolomics in this disorder and in the potential development of targeted therapies for precision medicine.

Identifiants

DOI: 10.1016/j.cca.2024.117850 PMID: 38431200
pubmed: 38431200
pii: S0009-8981(24)00091-3
doi: 10.1016/j.cca.2024.117850
pii:
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

117850

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Auteurs

Amos Victor Oluwaloseyi (A)

Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria; Anchor Biomed Research Institute, Ogbomoso, Oyo State, Nigeria.

Odeyemi Aduragbemi Noah (O)

Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Ajayi Lydia Oluwatoyin (A)

Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Yusuff Gaffar (Y)

Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Olotu Moses (O)

Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Akano Oyedayo Phillips (A)

Department of Physiology, Babcock University, Ilishan Remo, Ogun State, Nigeria.

Moyinoluwa Comfort Onaolapo (M)

Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria; Anchor Biomed Research Institute, Ogbomoso, Oyo State, Nigeria.

Bolade Sylvester Olateju (B)

Department of Nutrition and Integrative Physiology, Florida State University, USA.

Adelakun Ademola Ayodele (A)

Department of Medical Laboratory Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Oyowvi Mega Obukohwo (O)

Department of Physiology, Adeleke University, Ede, Osun State, Nigeria.

Ajayi Ayodeji Folorunsho (A)

Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria; Anchor Biomed Research Institute, Ogbomoso, Oyo State, Nigeria; Department of Physiology, Adeleke University, Ede, Osun State, Nigeria. Electronic address: aajayi22@lautech.edu.ng.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Metabolomics of male infertility.
questionsmedicales.fr › Maladies urogénitales › Maladies urogénitales de l'homme › Maladies de l'appareil génital mâle › Infertilité masculine › Metabolomics of male infertility.
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Metabolomics of male infertility.
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Métabolomique › Metabolomics of male infertility.
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Metabolomics of male infertility.