Structural Perspective of NR4A Nuclear Receptor Family and Their Potential Endogenous Ligands.
Homology Modeling of Complex Structure (HOMCOS)
endogenous ligand
ligand-binding domain
nuclear receptor subfamily 4 group A (NR4A)
prostaglandin A
template-based modeling
Journal
Biological & pharmaceutical bulletin
ISSN: 1347-5215
Titre abrégé: Biol Pharm Bull
Pays: Japan
ID NLM: 9311984
Informations de publication
Date de publication:
2024
2024
Historique:
medline:
4
3
2024
pubmed:
4
3
2024
entrez:
3
3
2024
Statut:
ppublish
Résumé
There are 48 nuclear receptors in the human genome, and many members of this superfamily have been implicated in human diseases. The NR4A nuclear receptor family consisting of three members, NR4A1, NR4A2, and NR4A3 (formerly annotated as Nur77, Nurr1, and NOR1, respectively), are still orphan receptors but exert pathological effects on immune-related and neurological diseases. We previously reported that prostaglandin A
Identifiants
pubmed: 38432913
doi: 10.1248/bpb.b23-00600
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM