Rifampicin adsorption and release study using Santa Barbara amorphous-16 modified Al (SBA-16-Al) for a drug delivery system.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
29 Feb 2024
Historique:
received: 07 12 2023
accepted: 18 02 2024
medline: 4 3 2024
pubmed: 4 3 2024
entrez: 4 3 2024
Statut: epublish

Résumé

In this study, the surface modification of Santa Barbara Amorphous-16 (SBA-16) with aluminum (SBA-16-Al) was carried out as a rifampicin matrix for the treatment of tuberculosis. Surface modification of SBA-16 was achieved using the direct-synthesis grafting method. Then, the adsorption and release properties of rifampicin from the SBA-16-Al matrix have been studied in batches. In addition, the SBA-16-Al has been characterized using Fourier-Transform Infrared Spectroscopy (FTIR), X-ray diffraction analysis (XRD), transmission electron microscopy (TEM), and Surface Area Analysis (SAA) Brunaur, Emmett and Teller (SAA-BET). The results show that the mesoporous material, the SBA-16-Al has a specific surface area of 843.5 m

Identifiants

pubmed: 38433940
doi: 10.1039/d3ra08360h
pii: d3ra08360h
pmc: PMC10906368
doi:

Types de publication

Journal Article

Langues

eng

Pagination

7371-7382

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

Auteurs

Maria Christina Prihatiningsih (MC)

Polytechnic Institute of Nuclear Technology, National Research and Innovation Agency (BRIN) Yogyakarta Indonesia maria.christina@polteknuklir.ac.id mari003@brin.go.id.

Chaidir Pratama (C)

Research Center for Radioisotope, Radiopharmaceutical, and Biodosimetry Technology, Research Organization of Nuclear Energy, National Research and Innovation Agency (BRIN) Indonesia.

Noor Anis Kundari (NA)

Polytechnic Institute of Nuclear Technology, National Research and Innovation Agency (BRIN) Yogyakarta Indonesia maria.christina@polteknuklir.ac.id mari003@brin.go.id.

Kartini Megasari (K)

Polytechnic Institute of Nuclear Technology, National Research and Innovation Agency (BRIN) Yogyakarta Indonesia maria.christina@polteknuklir.ac.id mari003@brin.go.id.

Dhita Ariyanti (D)

Polytechnic Institute of Nuclear Technology, National Research and Innovation Agency (BRIN) Yogyakarta Indonesia maria.christina@polteknuklir.ac.id mari003@brin.go.id.

Andri Saputra (A)

Department of Rubber and Plastic Processing Technology, Politeknik ATK Yogyakarta Indonesia.

Hersandy Dayu Kusuma (HD)

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran Jl. Raya Bandung - Sumedang KM. 21 Jatinangor Sumedang 45363 Indonesia.

Puji Astuti (P)

Polytechnic Institute of Nuclear Technology, National Research and Innovation Agency (BRIN) Yogyakarta Indonesia maria.christina@polteknuklir.ac.id mari003@brin.go.id.

Classifications MeSH