Papillary thyroid microcarcinoma with and without nodal metastasis: A comparative analysis.

lymph node metastasis papillary thyroid microcarcinoma risk factor thyroid cancer

Journal

Saudi medical journal
ISSN: 1658-3175
Titre abrégé: Saudi Med J
Pays: Saudi Arabia
ID NLM: 7909441

Informations de publication

Date de publication:
Mar 2024
Historique:
received: 27 08 2023
accepted: 15 01 2024
medline: 5 3 2024
pubmed: 5 3 2024
entrez: 4 3 2024
Statut: ppublish

Résumé

To assess the demographics and clinical factors of papillary thyroid microcarcinoma (PTMC) patients in Saudi Arabia and compared and analyzed the differences between the patients with and without lymph node metastasis (LNM). Papillary thyroid microcarcinoma (PTMC) is a common thyroid cancer and is not usually detectable clinically but found incidentally after pathologic evaluation of thyroid tissue following surgery for benign thyroid disorders. However, these tumors have a significant risk of LNM. All PTMC patients who underwent surgery at King Abdulaziz University Hospital, King Fahad Medical City, and King Abdulaziz Medical City from 2012 to 2022 were included. The incidence rate of LNM was 9.17%. The patients' average age was 44.05. Most of the patients were female. Prevalence of LNM among PTMC patients is 9.17% (n=31). The PTMC patients showed the following significant risk factors for LNM: higher Bethesda class, type of pathology, extrathyroidal extension, extracapsular extension, lymphovascular invasion, and residual tumors in patients who had received radioactive iodine. Presence of thyroiditis, multifocality, goitrous thyroid, neural invasion, and tumor size were unrelated to the LNM in the PTMC patients. Higher Bethesda class, pathology type, extrathyroidal extension, extracapsular extension, lymphovascular invasion, and RAI-treated residual tumors were strongly linked to LNM.

Identifiants

DOI: 10.15537/smj.2024.45.3.20230638 PMID: 38438216
pubmed: 38438216
pii: 45/3/267
doi: 10.15537/smj.2024.45.3.20230638
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

267-272

Informations de copyright

Copyright: © Saudi Medical Journal.

Auteurs

Saleh Alqaryan (S)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.
ORCID: 0000-0002-2393-0214

Hisham Almousa (H)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Raed Almutairi (R)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Ahmed Altuwaijri (A)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Aseel Doubi (A)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Zuhour Alqahtani (Z)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Mohammad Almayouf (M)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Majed Albarrak (M)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Mohammed Alessa (M)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Saleh Aldhahri (S)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Khalid Alqahtani (K)

From the Otolaryngology - Head and Neck Surgery Department (Alqaryan, Almousa, Alessa, Aldhahri, Alqahtani), King Saud University; from the Otolaryngology - Head and Neck Surgery Division, Department of Surgery (Alqaryan), King Abdulaziz Medical City, National Guard for Health Affairs; from the Otolaryngology - Head and Neck Surgery Department (Almayouf, Albarrak), King Fahad Medical City; from the Otolaryngology - Head and Neck Surgery Department (Doubi), King Saud Medical City; from the Otolaryngology - Head and Neck Surgery Department (Altuwaijri), Security Forces Hospital; from the College of Medicine (Alqahtani), Imam Mohammad Ibn Saud Islamic University, Riyadh; and from the Otolaryngology - Head and Neck Surgery Department (Almutairi), King Fahad Specialist Hospital, Buraidah, Kingdom of Saudi Arabia.

Classifications MeSH