Association of body mass index and blood pressure variability with 10-year mortality and renal disease progression in type 2 diabetes.

BMI variability Blood pressure variability Mortality Renal disease progression Type 2 diabetes

Journal

Acta diabetologica

ISSN: 1432-5233

Titre abrégé: Acta Diabetol

Pays: Germany

ID NLM: 9200299

Informations de publication

Date de publication:
04 Mar 2024

Historique:

received: 11 12 2023

accepted: 29 01 2024

medline: 5 3 2024

pubmed: 5 3 2024

entrez: 4 3 2024

Statut: aheadofprint

Résumé

Variability in biological parameters may be associated with adverse outcomes. The aim of the study was to determine whether variability in body mass index (BMI) and blood pressure is associated with all-cause, cardiovascular mortality and cancer mortality or with renal disease progression in subjects with type 2 diabetes. The diabetes database was accessed, and all the information on patient visits (consultations) carried out in the study period (1 January 2008-31 December 2019) was extracted and linked to the laboratory database and the mortality register. The total number of patients included in the study population was 26,261, of whom 54.4% were male. Median (interquartile range, IQR) age was 60.2 (51.8-68.3) years. The coefficient of variability of BMI was independently associated with increased all-cause and cardiovascular, but not cancer, mortality. Glycated haemoglobin (HbA Variability in BMI was associated with increased all-cause and cardiovascular, but not cancer, mortality in a large real-world contemporary population. Our results also confirm the association of HbA

Sections du résumé

BACKGROUND BACKGROUND

METHODS METHODS

The diabetes database was accessed, and all the information on patient visits (consultations) carried out in the study period (1 January 2008-31 December 2019) was extracted and linked to the laboratory database and the mortality register.

RESULTS RESULTS

The total number of patients included in the study population was 26,261, of whom 54.4% were male. Median (interquartile range, IQR) age was 60.2 (51.8-68.3) years. The coefficient of variability of BMI was independently associated with increased all-cause and cardiovascular, but not cancer, mortality. Glycated haemoglobin (HbA

CONCLUSIONS CONCLUSIONS

Variability in BMI was associated with increased all-cause and cardiovascular, but not cancer, mortality in a large real-world contemporary population. Our results also confirm the association of HbA

Identifiants

DOI: 10.1007/s00592-024-02250-z PMID: 38438789

pubmed: 38438789

doi: 10.1007/s00592-024-02250-z

pii: 10.1007/s00592-024-02250-z

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Informations de copyright

Références

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