Genotyping Immunology Transcriptomics

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
15 Mar 2024
Historique:
received: 18 10 2023
revised: 05 01 2024
accepted: 09 02 2024
medline: 5 3 2024
pubmed: 5 3 2024
entrez: 5 3 2024
Statut: epublish

Résumé

HLA-E molecules can present self- and pathogen-derived peptides to both natural killer (NK) cells and T cells. T cells that recognize HLA-E peptides via their T cell receptor (TCR) are termed donor-unrestricted T cells due to restricted allelic variation of HLA-E. The composition and repertoire of HLA-E TCRs is not known so far. We performed TCR sequencing on CD8

Identifiants

DOI: 10.1016/j.isci.2024.109233 PMID: 38439958 PMC: PMC10909886
pubmed: 38439958
doi: 10.1016/j.isci.2024.109233
pii: S2589-0042(24)00454-1
pmc: PMC10909886
doi:

Types de publication

Journal Article

Langues

eng

Pagination

109233

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no competing interest.

Auteurs

Linda Voogd (L)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Anne M H F Drittij (AMHF)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Calinda K E Dingenouts (CKE)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Kees L M C Franken (KLMC)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Vincent van Unen (VV)

Institute of Immunity, Transplantation and Infection, Stanford University School of Medicine, Palo Alto, CA, USA.

Krista E van Meijgaarden (KE)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Paula Ruibal (P)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Renate S Hagedoorn (RS)

Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.

Judith A Leitner (JA)

Centre for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.

Peter Steinberger (P)

Centre for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.

Mirjam H M Heemskerk (MHM)

Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.

Mark M Davis (MM)

Institute of Immunity, Transplantation and Infection, Stanford University School of Medicine, Palo Alto, CA, USA.
Howard Hughes Medical Institute, Stanford University School of Medicine, Palo Alto, CA, USA.

Thomas J Scriba (TJ)

South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.

Tom H M Ottenhoff (THM)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Simone A Joosten (SA)

Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.

Classifications MeSH