Use of Magnetic Resonance Imaging for Visualization of Oral Dosage Forms in the Human Stomach: A Scoping Review.

MRI MRI contrast agents MRI contrast markers dosage form disintegration fasted stomach fed stomach in vivo magnetic resonance imaging oral dosage forms oral drug delivery stomach

Journal

Molecular pharmaceutics
ISSN: 1543-8392
Titre abrégé: Mol Pharm
Pays: United States
ID NLM: 101197791

Informations de publication

Date de publication:
05 Mar 2024
Historique:
medline: 5 3 2024
pubmed: 5 3 2024
entrez: 5 3 2024
Statut: aheadofprint

Résumé

Oral dosage forms are the most widely and frequently used formulations to deliver active pharmaceutical ingredients (APIs), due to their ease of administration and noninvasiveness. Knowledge of intragastric release rates and gastric mixing is crucial for predicting the API release profile, especially for immediate release formulations. However, knowledge of the intragastric fate of oral dosage forms

Identifiants

pubmed: 38440796
doi: 10.1021/acs.molpharmaceut.3c01123
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Tejal Akbar (T)

Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, U.K.

Pavel Gershkovich (P)

School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, U.K.

Konstantinos Stamatopoulos (K)

Drug Product Development, GSK R&D, Ware, Hertfordshire SG12 0GX, U.K.

Penny A Gowland (PA)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2QX, U.K.

Snow Stolnik (S)

School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, U.K.

James Butler (J)

Drug Product Development, GSK R&D, Ware, Hertfordshire SG12 0GX, U.K.

Luca Marciani (L)

Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, U.K.

Classifications MeSH