Association between of vitamin B12 status during pregnancy and probable postpartum depression: the ECLIPSES study.
ECLIPSES study
Vitamin B12 levels
maternal health
postpartum depression
prenatal nutrition
Journal
Journal of reproductive and infant psychology
ISSN: 1469-672X
Titre abrégé: J Reprod Infant Psychol
Pays: England
ID NLM: 8501885
Informations de publication
Date de publication:
05 Mar 2024
05 Mar 2024
Historique:
medline:
5
3
2024
pubmed:
5
3
2024
entrez:
5
3
2024
Statut:
aheadofprint
Résumé
B12 vitamin is essential for the functioning of the nervous system and the production of mood-related neurotransmitters. However, information on its association with postpartum depression (PPD) is limited. To examine the effect of serum vitamin B12 levels during pregnancy on PPD, in healthy pregnant women from the Mediterranean region of Catalonia, Spain. This longitudinal study included a subsample of women at 54 days (7.7 weeks) postpartum ( The prevalence of probable PPD was 21%. After adjusting for sociodemographic, lifestyle, biochemical parameters, and postpartum characteristics the regression model showed a negative association between EPDS scores and the highest quartile of serum vitamin B12 (first quartile (reference) vs. fourth quartile), (β = -1.267, 95% CI = -2.461, -0.073, Maintaining a normal-high level of vitamin B12 during early pregnancy can contributes to preventing PPD.
Sections du résumé
BACKGROUND
UNASSIGNED
B12 vitamin is essential for the functioning of the nervous system and the production of mood-related neurotransmitters. However, information on its association with postpartum depression (PPD) is limited.
OBJECTIVE
UNASSIGNED
To examine the effect of serum vitamin B12 levels during pregnancy on PPD, in healthy pregnant women from the Mediterranean region of Catalonia, Spain.
METHOD
UNASSIGNED
This longitudinal study included a subsample of women at 54 days (7.7 weeks) postpartum (
RESULTS
UNASSIGNED
The prevalence of probable PPD was 21%. After adjusting for sociodemographic, lifestyle, biochemical parameters, and postpartum characteristics the regression model showed a negative association between EPDS scores and the highest quartile of serum vitamin B12 (first quartile (reference) vs. fourth quartile), (β = -1.267, 95% CI = -2.461, -0.073,
CONCLUSION
UNASSIGNED
Maintaining a normal-high level of vitamin B12 during early pregnancy can contributes to preventing PPD.
Identifiants
pubmed: 38440867
doi: 10.1080/02646838.2024.2324043
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM