Predictors and concomitants of the remission of frequent headache in pediatrics: A longitudinal community study.
adolescents
chronic pain
frequent headache
longitudinal
pediatric
remission
Journal
Headache
ISSN: 1526-4610
Titre abrégé: Headache
Pays: United States
ID NLM: 2985091R
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
revised:
04
01
2024
received:
17
05
2023
accepted:
08
01
2024
pubmed:
5
3
2024
medline:
5
3
2024
entrez:
5
3
2024
Statut:
ppublish
Résumé
We aimed to examine factors associated with frequent headache remission in schoolchildren aged 10-18 years. Frequent headache is a common health problem in adolescence, and some individuals in this population experience remission. Factors preceding headache remission as opposed to ongoing headache, and their development over time, have not been examined extensively. Data were derived from a large school sample (N = 2280). Over the course of 1 year, n = 156 adolescents experienced remission from frequent headaches, while n = 125 adolescents continued to have frequent headaches throughout the year. In this longitudinal case-control study, we predicted headache remission using demographic, pain, psychosocial, sleep, and physiological characteristics. Additionally, we sought to explore the development of psychosocial, sleep, and physiological characteristics in relation to remitted versus ongoing headache over the 1-year period. A model containing the variables sex (odds ratio [OR] = 0.43, 95% confidence interval [CI] = 0.248-0.76, p = 0.003), headache intensity (OR = 0.85, 95% CI = 0.73-0.99, p = 0.035), anxiety score (OR = 0.92, 95% CI = 0.85-1.01, p = 0.071), and depression score (OR = 0.94, 95% CI = 0.89-1.00, p = 0.041) predicted the outcome variable (remitted vs. non-remitted headache), explaining 17% of the variance in group membership. Schoolchildren reporting remitted headache at the end of the year exhibited lower depression (F[1, 557.01] = 45.77, p < 0.001) and anxiety scores (F[1, 557.01] = 21.72, p < 0.001), higher school satisfaction (F[1, 209.46] = 7.15, p = 0.008), and fewer difficulties falling asleep (F[1, 856.52] = 41.21, p < 0.001) or sleeping through the night (F[1, 731.12] = 26.42, p < 0.001) throughout the year compared to those with non-remitted headache. Depression scores declined significantly over the year in the group with remitted headache, whereas these scores remained constant in the group with non-remitted headache. Our results suggest a correlation between headache remission and male sex, improved mental health, and reduced pain-related burden. Moreover, there was an observed decline in symptoms of depression during headache remission. Psychotherapy may be a promising treatment strategy for addressing frequent headaches reported by children and adolescents.
Sections du résumé
OBJECTIVE
OBJECTIVE
We aimed to examine factors associated with frequent headache remission in schoolchildren aged 10-18 years.
BACKGROUND
BACKGROUND
Frequent headache is a common health problem in adolescence, and some individuals in this population experience remission. Factors preceding headache remission as opposed to ongoing headache, and their development over time, have not been examined extensively.
METHODS
METHODS
Data were derived from a large school sample (N = 2280). Over the course of 1 year, n = 156 adolescents experienced remission from frequent headaches, while n = 125 adolescents continued to have frequent headaches throughout the year. In this longitudinal case-control study, we predicted headache remission using demographic, pain, psychosocial, sleep, and physiological characteristics. Additionally, we sought to explore the development of psychosocial, sleep, and physiological characteristics in relation to remitted versus ongoing headache over the 1-year period.
RESULTS
RESULTS
A model containing the variables sex (odds ratio [OR] = 0.43, 95% confidence interval [CI] = 0.248-0.76, p = 0.003), headache intensity (OR = 0.85, 95% CI = 0.73-0.99, p = 0.035), anxiety score (OR = 0.92, 95% CI = 0.85-1.01, p = 0.071), and depression score (OR = 0.94, 95% CI = 0.89-1.00, p = 0.041) predicted the outcome variable (remitted vs. non-remitted headache), explaining 17% of the variance in group membership. Schoolchildren reporting remitted headache at the end of the year exhibited lower depression (F[1, 557.01] = 45.77, p < 0.001) and anxiety scores (F[1, 557.01] = 21.72, p < 0.001), higher school satisfaction (F[1, 209.46] = 7.15, p = 0.008), and fewer difficulties falling asleep (F[1, 856.52] = 41.21, p < 0.001) or sleeping through the night (F[1, 731.12] = 26.42, p < 0.001) throughout the year compared to those with non-remitted headache. Depression scores declined significantly over the year in the group with remitted headache, whereas these scores remained constant in the group with non-remitted headache.
CONCLUSION
CONCLUSIONS
Our results suggest a correlation between headache remission and male sex, improved mental health, and reduced pain-related burden. Moreover, there was an observed decline in symptoms of depression during headache remission. Psychotherapy may be a promising treatment strategy for addressing frequent headaches reported by children and adolescents.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
306-316Subventions
Organisme : German Federal Ministry of Education and Research
ID : 01GY1615
Informations de copyright
© 2024 The Authors. Headache: The Journal of Head and Face Pain published by Wiley Periodicals LLC on behalf of American Headache Society.
Références
Fendrich K, Vennemann M, Pfaffenrath V, et al. Headache prevalence among adolescents: the German DMKG headache study. Cephalalgia. 2007;27:347-354.
Philipp J, Zeiler M, Wöber C, et al. Prevalence and burden of headache in children and adolescents in Austria: a nationwide study in a representative sample of pupils aged 10-18 years. J Headache Pain. 2019;20:101.
Wager J, Brown DT, Kupitz A, Rosenthal N, Zernikow B. Prevalence and associated psychosocial and health factors of chronic pain in adolescents: differences by sex and age. Eur J Pain. 2020;24:761-772.
Gobina I, Villberg J, Välimaa R, et al. Prevalence of self-reported chronic pain among adolescents: evidence from 42 countries and regions. Eur J Pain. 2019;23:316-326.
Haraldstad K, Sørum R, Eide H, Natvig GK, Helseth S. Pain in children and adolescents: prevalence, impact on daily life, and parents' perception, a school survey. Scand J Caring Sci. 2011;25:27-36.
Alp R, Alp SI, Palanci Y, et al. Use of the international classification of headache disorders, second edition, criteria in the diagnosis of primary headache in schoolchildren: epidemiology study from eastern Turkey. Cephalalgia. 2010;30:868-877.
Sillanpää M, Saarinen MM. Long term outcome of childhood onset headache: a prospective community study. Cephalalgia. 2018;38:1159-1166.
Guidetti V, Galli F. Evolution of headache in childhood and adolescence: an 8-year follow-up. Cephalalgia. 1998;18:449-454.
Knestrick KE, Gibler RC, Reidy BL, Powers SW. Psychological interventions for pediatric headache disorders: a 2021 update on research progress and needs. Curr Pain Headache Rep. 2022;26:85-91.
Termine C, Ferri M, Livetti G, et al. Migraine with aura with onset in childhood and adolescence: long-term natural history and prognostic factors. Cephalalgia. 2010;30:674-681.
Ellert U, Neuhauser H, Roth-Isigkeit A. Schmerzen bei Kindern und Jugendlichen in Deutschland: Prävalenz und Inanspruchnahme medizinischer Leistungen. Ergebnisse des Kinder- und Jugendgesundheitssurveys (KiGGS). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007;50:711-717.
Carasco M, Kröner-Herwig B. Psychological predictors of headache remission in children and adolescents. Adolesc Health Med Ther. 2016;7:59-66.
Gatchel RJ, Peng YB, Peters ML, Fuchs PN, Turk DC. The biopsychosocial approach to chronic pain: scientific advances and future directions. Psychol Bull. 2007;133:581-624.
Skrove M, Romundstad P, Indredavik MS. Chronic multisite pain in adolescent girls and boys with emotional and behavioral problems: the young-HUNT study. Eur Child Adolesc Psychiatry. 2015;24:503-515.
Stanford EA, Chambers CT, Biesanz JC, Chen E. The frequency, trajectories and predictors of adolescent recurrent pain: a population-based approach. Pain. 2008;138:11-21.
Rhee H. Prevalence and predictors of headaches in US adolescents. Headache. 2000;40:528-538.
King S, Chambers CT, Huguet A, et al. The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain. 2011;152:2729-2738.
Caponnetto V, Deodato M, Robotti M, et al. Comorbidities of primary headache disorders: a literature review with meta-analysis. J Headache Pain. 2021;22:71.
Gordon KE, Dooley JM, Wood EP. Self-reported headache frequency and features associated with frequent headaches in Canadian young adolescents. Headache. 2004;44:555-561.
Luntamo T, Sourander A, Rihko M, et al. Psychosocial determinants of headache, abdominal pain, and sleep problems in a community sample of Finnish adolescents. Eur Child Adolesc Psychiatry. 2012;21:301-313.
Robberstad L, Dyb G, Hagen K, Stovner LJ, Holmen TL, Zwart JA. An unfavorable lifestyle and recurrent headaches among adolescents: the HUNT study. Neurology. 2010;75:712-717.
Brown DT, Rosenthal N, Könning A, Wager J. Intergenerational transmission of chronic pain-related disability: the explanatory effects of depressive symptoms. Pain. 2021;162:653-662.
Brown DT, Claus BB, Könning A, Wager J. Unified multifactorial model of parental factors in community-based pediatric chronic pain. J Pediatr Psychol. 2022;47:121-131.
Könning A, Rosenthal N, Brown DT, Stahlschmidt L, Wager J. Severity of chronic pain in German adolescent school students: a cross-sectional study. Clin J Pain. 2021;37:118-125.
Könning A, Rosenthal N, Friese M, Hirschfeld G, Brown D, Wager J. Factors associated with physician consultation and medication use in children and adolescents with chronic pain: a scoping review and original data. Eur J Pain. 2021;25:88-106.
Neß V, Könning A, Hirschfeld G, Wager J. Adolescents' explanatory models for headaches and associations with behavioral and emotional outcomes. Children. 2021;8:234.
Schroeder S, Hechler T, Denecke H, et al. Deutscher Schmerzfragebogen für Kinder, Jugendliche und deren Eltern (DSF-KJ): Entwicklung und Anwendung eines multimodalen Fragebogens zur Diagnostik und Therapie chronischer Schmerzen im Kindes- und Jugendalter. Der Schmerz. 2010;24:23-37.
Hoftun GB, Romundstad PR, Zwart J-A, Rygg M. Chronic idiopathic pain in adolescence: high prevalence and disability. The young HUNT Study 2008. Pain. 2011;152:2259-2266.
Varni JW, Thompson KL, Hanson V. The Varni/Thompson pediatric pain questionnaire: I. Chronic musculoskeletal pain in juvenile rheumatoid arthritis. Pain. 1987;28:27-38.
Hübner B, Hechler T, Dobe M, et al. Schmerzbezogene Beeinträchtigung bei Jugendlichen mit chronischen Schmerzen: Erste Uberprüfung des Pediatric Pain Disability Index (P-PDI). Schmerz. 2009;23:20-32.
Wager J, Tietze A-L, Denecke H, et al. Schmerzempfindung bei Jugendlichen mit chronischen funktionellen Schmerzen: adaptation und psychometrische Uberprüfung der Schmerzempfindungsskala (SES) nach Geissner. Der Schmerz. 2010;24:236-250.
Chorpita BF, Yim L, Moffitt C, Umemoto LA, Francis SE. Assessment of symptoms of DSM-IV anxiety and depression in children: a revised child anxiety and depression scale. Behav Res Ther. 2000;38:835-855.
Stahlschmidt L, Chorpita BF, Wager J. Validating the German version of the Revised Children's Anxiety and Depression Scale in a sample of pediatric chronic pain patients. J Psychosom Res. 2019;124:109786.
Ravens-Sieberer U, Gosch A, Rajmil L, et al. The KIDSCREEN-52 quality of life measure for children and adolescents: psychometric results from a cross-cultural survey in 13 European countries. Value Health. 2008;11:645-658.
R Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing; 2022.
RStudio Team. RStudio: Integrated Development Environment for R. RStudio, PBC; 2022. http://www.rstudio.com/
van Buuren S. Flexible Imputation of Missing Data. CRC Press; 2018.
Rubin DB. Multiple Imputation for Nonresponse in Surveys. John Wiley & Sons; 1987.
Marshall A, Altman DG, Holder RL, Royston P. Combining estimates of interest in prognostic modelling studies after multiple imputation: current practice and guidelines. BMC Med Res Methodol. 2009;9:57.
Li KH, Raghunathan TE, Rubin DB. Large-sample significance levels from multiply imputed data using moment-based statistics and an F reference distribution. J Am Stat Assoc. 1991;86:1065-1073.
Rosner B, Muñoz A, Tager I, Speizer F, Weiss S. The use of an autoregressive model for the analysis of longitudinal data in epidemiologic studies. Stat Med. 1985;4:457-467.
Sawilowsky SS. New effect size rules of thumb. J Mod App Stat Meth. 2009;8:597-599.
Haack M, Simpson N, Sethna N, Kaur S, Mullington J. Sleep deficiency and chronic pain: potential underlying mechanisms and clinical implications. Neuropsychopharmacology. 2020;45:205-216.
Amundson GJG, Noel M, Petter M, et al. Pediatric fear-avoidance model of chronic pain: foundation, application and future directions. Pain Res Manage. 2012;17:397-405.
Pine DS, Cohen P, Brook J. The association between major depression and headache: results of a longitudinal epidemiologic study in youth. J Child Adolesc Psychopharmacol. 1996;6:153-164.
Larsson B, Sund AM. Emotional/behavioural, social correlates and one-year predictors of frequent pains among early adolescents: influences of pain characteristics. Eur J Pain. 2007;11:57-65.
Fishbain DA, Cutler R, Rosomoff HL, Rosomoff RS. Chronic pain-associated depression: antecedent or consequence of chronic pain? A review. Clin J Pain. 1997;13:116-137.
Altman DG, Royston P. The costs of dichotomising continuous variables. BMJ. 2006;332:1080.