Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse.
cell biology
flagellum
genetics
genomics
human
infertility
mouse
sperm
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
05 Mar 2024
05 Mar 2024
Historique:
medline:
5
3
2024
pubmed:
5
3
2024
entrez:
5
3
2024
Statut:
epublish
Résumé
From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the
Identifiants
pubmed: 38441556
doi: 10.7554/eLife.86845
pii: 86845
doi:
pii:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : European Research Council
ID : 715289
Pays : International
Informations de copyright
© 2023, Muroňová, Kherraf et al.
Déclaration de conflit d'intérêts
JM, ZK, EG, EL, SE, CC, AA, MC, GC, GM, YN, FK, LW, NK, VH, LD, JE, PG, CC, SM, MK, AB, RZ, NT, SN, SG, CL, PR, CA No competing interests declared