Image-guided biopsy of intracranial lesions in children, with a small robotic device: a case series.

Autoguide Brain tumors Pediatric tumors Robotics Stereotactic biopsy

Journal

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
ISSN: 1433-0350
Titre abrégé: Childs Nerv Syst
Pays: Germany
ID NLM: 8503227

Informations de publication

Date de publication:
05 Mar 2024
Historique:
received: 04 02 2024
accepted: 28 02 2024
medline: 5 3 2024
pubmed: 5 3 2024
entrez: 5 3 2024
Statut: aheadofprint

Résumé

Robot-assisted biopsies have gained popularity in the last years. Most robotic procedures are performed with a floor-based robotic arm. Recently, Medtronic Stealth Autoguide, a miniaturized robotic arm that work together with an optical neuronavigation system, was launched. Its application in pediatric cases is relatively unexplored. In this study, we retrospectively report our experience using the Stealth Autoguide, for frameless stereotactic biopsies in pediatric patients. Pediatric patients who underwent stereotactic biopsy using the Stealth Autoguide cranial robotic platform from July 2020 to May 2023 were included in this study. Clinical, neuroradiological, surgical, and histological data were collected and analyzed. Nineteen patients underwent 20 procedures (mean age was 9-year-old, range 1-17). In four patients, biopsy was part of a more complex surgical procedure (laser interstitial thermal therapy - LITT). The most common indication was diffuse intrinsic brain stem tumor, followed by diffuse supratentorial tumor. Nine procedures were performed in prone position, eight in supine position, and three in lateral position. Facial surface registration was adopted in six procedures, skull-fixed fiducials in 14. The biopsy diagnostic tissue acquisition rate was 100% in the patients who underwent only biopsy, while in the biopsy/LITT group, one case was not diagnostic. No patients developed clinically relevant postoperative complications. The Stealth Autoguide system has proven to be safe, diagnostic, and highly accurate in performing stereotactic biopsies for both supratentorial and infratentorial lesions in the pediatric population.

Sections du résumé

BACKGROUND AND OBJECTIVES OBJECTIVE
Robot-assisted biopsies have gained popularity in the last years. Most robotic procedures are performed with a floor-based robotic arm. Recently, Medtronic Stealth Autoguide, a miniaturized robotic arm that work together with an optical neuronavigation system, was launched. Its application in pediatric cases is relatively unexplored. In this study, we retrospectively report our experience using the Stealth Autoguide, for frameless stereotactic biopsies in pediatric patients.
METHODS METHODS
Pediatric patients who underwent stereotactic biopsy using the Stealth Autoguide cranial robotic platform from July 2020 to May 2023 were included in this study. Clinical, neuroradiological, surgical, and histological data were collected and analyzed.
RESULTS RESULTS
Nineteen patients underwent 20 procedures (mean age was 9-year-old, range 1-17). In four patients, biopsy was part of a more complex surgical procedure (laser interstitial thermal therapy - LITT). The most common indication was diffuse intrinsic brain stem tumor, followed by diffuse supratentorial tumor. Nine procedures were performed in prone position, eight in supine position, and three in lateral position. Facial surface registration was adopted in six procedures, skull-fixed fiducials in 14. The biopsy diagnostic tissue acquisition rate was 100% in the patients who underwent only biopsy, while in the biopsy/LITT group, one case was not diagnostic. No patients developed clinically relevant postoperative complications.
CONCLUSION CONCLUSIONS
The Stealth Autoguide system has proven to be safe, diagnostic, and highly accurate in performing stereotactic biopsies for both supratentorial and infratentorial lesions in the pediatric population.

Identifiants

pubmed: 38441630
doi: 10.1007/s00381-024-06349-0
pii: 10.1007/s00381-024-06349-0
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

Legnani FG, Franzini A, Mattei L et al (2019) Image-guided biopsy of intracranial lesions with a small robotic device (iSYS1): a prospective, exploratory pilot study. Operative Surg 17:403–412. https://doi.org/10.1093/ons/opy411
doi: 10.1093/ons/opy411
Kojima Y, Uda T, Kawashima T et al (2022) Primary experiences with robot-assisted navigation-based frameless stereo-electroencephalography: higher accuracy than neuronavigation-guided manual adjustment. Neurol Med Chir (Tokyo) 62:361–368. https://doi.org/10.2176/jns-nmc.2022-0010
doi: 10.2176/jns-nmc.2022-0010
Krieger MD, Chandrasoma PT, Zee C-S, Apuzzo MLJ (1998) Role of stereotactic biopsy in the diagnosis and management of brain tumors. Semin Surg Oncol 14:13–25. https://doi.org/10.1002/(SICI)1098-2388(199801/02)14:1%3c13::AID-SSU3%3e3.0.CO;2-5
doi: 10.1002/(SICI)1098-2388(199801/02)14:1<13::AID-SSU3>3.0.CO;2-5
Ma F-Z, Liu D-F, Yang A-C et al (2022) Application of the robot-assisted implantation in deep brain stimulation. Front Neurorobot 16:996685. https://doi.org/10.3389/fnbot.2022.996685
doi: 10.3389/fnbot.2022.996685
Cardinale F (2016) Stereoelectroencephalography: application accuracy, efficacy, and safety. World Neurosurgery 94:570–571. https://doi.org/10.1016/j.wneu.2016.07.070
doi: 10.1016/j.wneu.2016.07.070
Gonzalez-Martinez J, Vadera S, Mullin J et al (2014) Robot-assisted stereotactic laser ablation in medically intractable epilepsy: operative technique. Operative Neurosurgery 10:167–173. https://doi.org/10.1227/NEU.0000000000000286
doi: 10.1227/NEU.0000000000000286
De Benedictis A, Trezza A, Carai A et al (2017) Robot-assisted procedures in pediatric neurosurgery. Neurosurg Focus 42:E7. https://doi.org/10.3171/2017.2.FOCUS16579
doi: 10.3171/2017.2.FOCUS16579
Haegelen C, Touzet G, Reyns N et al (2010) Stereotactic robot-guided biopsies of brain stem lesions: experience with 15 cases. Neurochirurgie 56:363–367. https://doi.org/10.1016/j.neuchi.2010.05.006
doi: 10.1016/j.neuchi.2010.05.006
Lefranc M, Capel C, Pruvot-Occean A-S et al (2015) Frameless robotic stereotactic biopsies: a consecutive series of 100 cases. JNS 122:342–352. https://doi.org/10.3171/2014.9.JNS14107
doi: 10.3171/2014.9.JNS14107
Varma TRK, Eldridge P (2006) Use of the NeuroMate stereotactic robot in a frameless mode for functional neurosurgery. Int J Med Robotics Comput Assist Surg 2:107–113. https://doi.org/10.1002/rcs.88
doi: 10.1002/rcs.88
Kreatsoulas DC, Vignolles-Jeong J, Ambreen Y et al (2023) Surgical characteristics of intracranial biopsy using a frameless stereotactic robotic platform: a single-center experience. Operative Neurosurgery. https://doi.org/10.1227/ons.0000000000000999
doi: 10.1227/ons.0000000000000999
Früh A, Schaumann A, Cohrs G et al (2023) Biopsies of caudal brainstem tumors in pediatric patients—a single-center retrospective case series. World Neurosurgery 177:e84–e93. https://doi.org/10.1016/j.wneu.2023.05.108
doi: 10.1016/j.wneu.2023.05.108
Alexander H, Fayed I, Oluigbo CO (2020) Rigid cranial fixation for robot-assisted stereoelectroencephalography in toddlers: technical considerations. Operative Surg 18:614–620. https://doi.org/10.1093/ons/opz247
doi: 10.1093/ons/opz247
Sickler RW, Chandran AS, Funke ME et al (2023) Comparison of 2 robotic systems for pediatric stereoelectroencephalography implantation. World Neurosurgery 182:e486–e492. https://doi.org/10.1016/j.wneu.2023.11.125
doi: 10.1016/j.wneu.2023.11.125
Niznik T, Grossen A, Shi H et al (2023) Learning curve in robotic stereoelectroencephalography: single platform experience. World Neurosurgery 182:e442–e452. https://doi.org/10.1016/j.wneu.2023.11.119
doi: 10.1016/j.wneu.2023.11.119
Minchev G, Kronreif G, Martínez-Moreno M et al (2017) A novel miniature robotic guidance device for stereotactic neurosurgical interventions: preliminary experience with the iSYS1 robot. JNS 126:985–996. https://doi.org/10.3171/2016.1.JNS152005
doi: 10.3171/2016.1.JNS152005
Fomenko A, Serletis D (2018) Robotic stereotaxy in cranial neurosurgery: a qualitative systematic review. Neurosurgery 83:642–650. https://doi.org/10.1093/neuros/nyx576
doi: 10.1093/neuros/nyx576

Auteurs

Pietro Spennato (P)

Department of Neurosciences, Division of Neurosurgery, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80121, Naples, Italy. pierospen@gmail.com.

Marianna Di Costanzo (M)

Department of Neurosciences, Division of Neurosurgery, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80121, Naples, Italy.
Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Università degli Studi di Napoli "Federico II", Naples, Italy.

Giuseppe Mirone (G)

Department of Neurosciences, Division of Neurosurgery, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80121, Naples, Italy.

Domenico Cicala (D)

Department of Neurosciences, Division of Neuroradiology, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Lucia De Martino (L)

Department of Onco-Hematology, Unit of Neuro-oncology, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Nicola Onorini (N)

Department of Neurosciences, Division of Neurosurgery, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80121, Naples, Italy.

Claudio Ruggiero (C)

Department of Neurosciences, Division of Neurosurgery, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80121, Naples, Italy.

Giuseppe Cinalli (G)

Department of Neurosciences, Division of Neurosurgery, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80121, Naples, Italy.

Classifications MeSH