Wearable activity tracker study exploring rheumatoid arthritis patients' disease activity using patient-reported outcome measures, clinical measures, and biometric sensor data (the wear study).
Mobile technology
Patient-generated health data
Patient-reported outcomes
Patients
Real world data
Real world evidence
Rheumatoid arthritis
Wearable digital technology
Journal
Contemporary clinical trials communications
ISSN: 2451-8654
Titre abrégé: Contemp Clin Trials Commun
Pays: Netherlands
ID NLM: 101671157
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
received:
21
03
2023
revised:
02
02
2024
accepted:
13
02
2024
medline:
6
3
2024
pubmed:
6
3
2024
entrez:
6
3
2024
Statut:
epublish
Résumé
Digital health studies using electronic patient reported outcomes (ePROs), wearables, and clinical data to provide a more comprehensive picture of patient health. Newly initiated patients on upadacitinib or adalimumab for RA will be recruited from community settings in the Excellence NEtwork in RheumatoloGY (ENRGY) practice-based research network. Over the period of three to six months, three streams of data will be collected (1) linkable physician-derived data; (2) self-reported daily and weekly ePROs through the ArthritisPower registry app; and (3) biometric sensor data passively collected via wearable. These data will be analyzed to evaluate correlations among the three types of data and patient improvement on the newly initiated medication. Results from this study will provide valuable information regarding the relationships between physician data, wearable data, and ePROs in patients newly initiating an RA treatment, and demonstrate the feasibility of digital data capture for Remote Patient Monitoring of patients with rheumatic disease.
Sections du résumé
Background
UNASSIGNED
Digital health studies using electronic patient reported outcomes (ePROs), wearables, and clinical data to provide a more comprehensive picture of patient health.
Methods
UNASSIGNED
Newly initiated patients on upadacitinib or adalimumab for RA will be recruited from community settings in the Excellence NEtwork in RheumatoloGY (ENRGY) practice-based research network. Over the period of three to six months, three streams of data will be collected (1) linkable physician-derived data; (2) self-reported daily and weekly ePROs through the ArthritisPower registry app; and (3) biometric sensor data passively collected via wearable. These data will be analyzed to evaluate correlations among the three types of data and patient improvement on the newly initiated medication.
Conclusions
UNASSIGNED
Results from this study will provide valuable information regarding the relationships between physician data, wearable data, and ePROs in patients newly initiating an RA treatment, and demonstrate the feasibility of digital data capture for Remote Patient Monitoring of patients with rheumatic disease.
Identifiants
pubmed: 38444876
doi: 10.1016/j.conctc.2024.101272
pii: S2451-8654(24)00019-X
pmc: PMC10912436
doi:
Types de publication
Journal Article
Langues
eng
Pagination
101272Informations de copyright
© 2024 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Global Healthy Living Foundation receives grants, sponsorships and contracts from pharmaceutical manufacturers and private foundations. A full list of GHLF funders is publicly available here: https://www.ghlf.org/our-partners/ PZ is employed by 10.13039/100006483AbbVie. JRC receives grants from 10.13039/100000960ACR, 10.13039/100006483AbbVie, 10.13039/100002429Amgen, ArthritisPower, Aqtual, Bendcare, 10.13039/100002491BMS, CorEvitas, FASTER, 10.13039/100004330GSK, IlluminationHealth, Janssen, Labcorp, 10.13039/100004312Lilly, 10.13039/100016939Myriad, 10.13039/100008272Novartis, 10.13039/100004319Pfizer, 10.13039/100004339Sanofi, Scipher, Setpoint, 10.13039/100006978UCB, United Rheumatology. He has received honorariums from 10.13039/100000960ACR, 10.13039/100006483Abbvie, 10.13039/100002429Amgen, ArthritisPower, Aqtual, Bendcare, BMS, CorEvitas, FASTER, GSK, IlluminationHealth, Janssen, Labcorp, 10.13039/100004312Lilly Myriad, 10.13039/100004336Novartis, Revero, 10.13039/100004319Pfizer, 10.13039/100004339Sanofi, Scipher, Setpoint, TNacity, Blue Ocean, 10.13039/100006978UCB.