Are carfentanil and acrylfentanyl naloxone resistant?
fentanyl
in vitro
naloxone
opioid
overdose
Journal
Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006
Informations de publication
Date de publication:
2024
2024
Historique:
received:
22
12
2023
accepted:
25
01
2024
medline:
6
3
2024
pubmed:
6
3
2024
entrez:
6
3
2024
Statut:
epublish
Résumé
The rapid rise in deaths since 2012 due to opioid poisoning is correlated with the proliferation of potent synthetic opioid agonists such as fentanyl, acrylfentanyl, and carfentanil. The efficacy of frontline antidotes such as naloxone in reversing such poisoning events has been questioned, and the possibility of naloxone-resistant synthetic opioids has been raised. In this manuscript, we applied
Identifiants
pubmed: 38445085
doi: 10.3389/fpsyt.2024.1359851
pmc: PMC10912486
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1359851Informations de copyright
Copyright © 2024 Feasel, Moran, Cheng and Averick.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.