Unveiling the Hidden Stroke Threat in Patients with Atrial Fibrillation and Primary Hyperparathyroidism.

Recent ACC/AHA/ACCP/HRS guidelines suggest that patients with Atrial fibrillation (AF) at intermediate to low annual risk of ischemic stroke can benefit from consideration of factors that might modify their risk of stroke. The role of non-traditional risk factors such as primary hyperparathyroidism (PHPT) remains unexplored. In our study, we investigated the potential association between PHPT and the risk of ischemic stroke among patients with AF. Using data from the Nationwide Inpatient Sample Database, a retrospective cohort study focused on the adult population with AF and stratified them based on PHPT presence. Demographic information, comorbidities, and hospitalization details were extracted using ICD-10 codes. Propensity score matching was applied, encompassing over 20 confounding variables, including the risk factors outlined in the CHA

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Declaration of competing interest The authors declare that they have no competing interests to report.