Leishmaniasis in otorhinolaryngology: an emerging disease and its relationship with anti-tumor necrosis factor-alpha drugs.

Anti-TNF alpha Emerging disease Leishmania Leishmaniasis Otorhinolaryngology

Journal

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937

Informations de publication

Date de publication:
08 Mar 2024
Historique:
received: 07 01 2024
accepted: 18 02 2024
medline: 8 3 2024
pubmed: 8 3 2024
entrez: 7 3 2024
Statut: aheadofprint

Résumé

To investigate the clinical manifestations, management and outcomes of Leishmania lesions in the ear-nose-throat (ENT) region, and its relationship with tumor necrosis factor (TNF)-α blocking drugs. Single-center retrospective observational study. Patients diagnosed with cutaneous and mucosal leishmaniasis in the otorhinolaryngologic area at a tertiary referral center over a period of 8 years. Three cases of Leishmania lesions in the ear and two in the nose were encountered at our institution. All patients were under treatment with TNF-α blocking drugs. Diagnosis was challenging, and it was important to have a clinical suspicion in order to use accurate detection techniques. All patients received systemic treatment and achieved a complete resolution of the lesions. With the increasing use of biologic treatments like TNF-α blockers, this type of infection will be increasingly frequent in endemic areas and also worldwide. It is important to include leishmaniasis in the differential diagnosis of inflammatory/infectious lesions in the ENT region.

Identifiants

DOI: 10.1007/s00405-024-08569-1 PMID: 38453713
pubmed: 38453713
doi: 10.1007/s00405-024-08569-1
pii: 10.1007/s00405-024-08569-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Anna Penella (A)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain. apenella@bellvitgehospital.cat.
Departament de Ciències Clíniques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Feixa Llarga s/n, 08907, L'Hospitalet de Llobregat, Spain. apenella@bellvitgehospital.cat.
ORCID: 0000-0003-0100-4807

Clara Muntaner-Virgili (C)

Dermatology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.

Joaquim Marcoval (J)

Dermatology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.

Xavier González-Compta (X)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.
Departament de Ciències Clíniques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Feixa Llarga s/n, 08907, L'Hospitalet de Llobregat, Spain.

Marta Mesalles-Ruiz (M)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.
Departament de Ciències Clíniques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Feixa Llarga s/n, 08907, L'Hospitalet de Llobregat, Spain.

Miguel García Wagner (M)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.

Francesc Cruellas (F)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.

Miriam Hamdan (M)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.
Departament de Ciències Clíniques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Feixa Llarga s/n, 08907, L'Hospitalet de Llobregat, Spain.

Julio Nogués (J)

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.

Jaime Notario (J)

Dermatology Department, Hospital Universitari de Bellvitge, Universitat de Barcelona (UB), IDIBELL, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Spain.

Classifications MeSH