α-Glucosidase Inhibitory Components from Garcinia pedunculata Fruits.
Garcinia pedunculata, α-glucosidase, molecular docking
Journal
Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449
Informations de publication
Date de publication:
09 Mar 2024
09 Mar 2024
Historique:
revised:
07
03
2024
received:
16
02
2024
accepted:
08
03
2024
medline:
9
3
2024
pubmed:
9
3
2024
entrez:
9
3
2024
Statut:
aheadofprint
Résumé
From Garcinia pedunculata Roxb. fruits, two undescribed aromatic compounds including a benzofuran and a depsidone derivative, and a new natural product, together with four known compounds were isolated. Through the analysis of spectroscopic data, high resolution mass spectrum and calculated nuclear magnetic resonance, their structures were determined. The α-glucosidase inhibitory activity of the isolates was evaluated. And compound 3 exhibited a moderate inhibitory effect on α-glucosidase. The molecular docking of compound 3 was performed to elucidate the interaction with α-glucosidase.
Identifiants
pubmed: 38459792
doi: 10.1002/cbdv.202400409
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202400409Informations de copyright
© 2024 Wiley-VCH GmbH.