Plasma membrane calcium ATPase powered by glycolysis is the main mechanism for calcium clearance in the hippocampal pyramidal neuron.

Mitochondria Oxidative phosphorylation PMCA SERCA Sodium‑calcium exchanger Tricarboxylic acid cycle

Journal

Life sciences
ISSN: 1879-0631
Titre abrégé: Life Sci
Pays: Netherlands
ID NLM: 0375521

Informations de publication

Date de publication:
08 Mar 2024
Historique:
received: 25 12 2023
revised: 27 02 2024
accepted: 05 03 2024
pubmed: 11 3 2024
medline: 11 3 2024
entrez: 10 3 2024
Statut: aheadofprint

Résumé

This study sought to elucidate the primary ATP-dependent mechanisms involved in clearing cytosolic Ca Our investigation involved evaluating basal Ca Our findings unveiled that the plasma membrane Ca These findings underscore the vital role of glycolysis in bolstering PMCA neuronal function to uphold Ca

Identifiants

pubmed: 38462228
pii: S0024-3205(24)00143-7
doi: 10.1016/j.lfs.2024.122554
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

122554

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no conflict of interest.

Auteurs

Vitor S Alves (VS)

Cellular and Molecular Neurobiology Laboratory (LaNeC), Center for Mathematics, Computing and Cognition (CMCC), Federal University of ABC - UFABC, São Bernardo do Campo, SP, Brazil.

Fernando A Oliveira (FA)

Cellular and Molecular Neurobiology Laboratory (LaNeC), Center for Mathematics, Computing and Cognition (CMCC), Federal University of ABC - UFABC, São Bernardo do Campo, SP, Brazil. Electronic address: oliveira.fernando@ufabc.edu.br.

Classifications MeSH