Micronutrient deficiency and supplements in schoolchildren and teenagers.
Journal
Current opinion in clinical nutrition and metabolic care
ISSN: 1473-6519
Titre abrégé: Curr Opin Clin Nutr Metab Care
Pays: England
ID NLM: 9804399
Informations de publication
Date de publication:
11 Mar 2024
11 Mar 2024
Historique:
medline:
11
3
2024
pubmed:
11
3
2024
entrez:
11
3
2024
Statut:
aheadofprint
Résumé
The essential micronutrients are corner stones in the functional and physical development. Early deficiency has life-long consequences. While awareness about iron deficiency is relatively high, it remains lower for other micronutrients. This review aims at reporting on recent data and attracting attention to the high prevalence of micronutrient deficiencies in school-age and adolescent individuals. Iron deficiency anaemia remains highly prevalent worldwide and the most frequent deficiency but can be corrected with simple tools ranging from food fortification, nutritional intervention, and to supplements. The link between micronutrient (MN) deficiency and neurobehavioral disorders is increasingly established and is worrying even in Western countries. Paediatric individuals are prone to imbalanced diets and picky eating behaviour, and their diets may then become incomplete: the highest risk for deficiency is observed for iron, zinc and vitamin D. There is not much new information, but rather confirmation of the importance of health policies. Well conducted randomized controlled trials confirm that deficiencies can be corrected efficiently including with food fortification, and result in clinical benefits. Individual complementation should be considered in children and adolescents with proven deficiency.
Identifiants
pubmed: 38462972
doi: 10.1097/MCO.0000000000001027
pii: 00075197-990000000-00143
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
Références
Requirements Institute of Medicine (IOM). Child and Adult Care Food Program: Aligning Dietary Guidance for All. Washington (DC): National Academies Press (US); 2011.
EFSA. Overview on Dietary Reference Values for the EU population as derived by the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). EFSA journal 2017. https://www.efsa.europa.eu/sites/default/files/assets/DRV_Summary_tables_jan_17.pdf.
Taylor CM, Emmett PM. Picky eating in children: causes and consequences. Proc Nutr Soc 2019; 78:161–169.
Ara G, Little DC, Mamun AA, et al. Factors affecting the micronutrient status of adolescent girls living in complex agro-aquatic ecological zones of Bangladesh. Sci Rep 2023; 13:6631.
World, Health, Organisation, WHO. Multiple micronutrient powders for point-of-use fortification of foods consumed by children 2–12 years of age. Geneva: WHO; Licence: CC BY-NC-SA 3.0 IGO; 2016.
UNICEF, Section NaCD. Advancing large scale food fortification - UNICEF's vision and approach to persitent micronutrient deficiencies. https://www.unicef.org/media/110346/file/Advancing%20Large%20Scale%20Food%20Fortification.%20UNICEF's%20Vision%20and%20Approach.pdf. 2021. pp. 1-15.
Cole CR. Preventing hidden hunger in children using micronutrient supplementation. J Pediatr 2012; 161:777–778.
Sichert-Hellert W, Wenz G, Kersting M. Vitamin intakes from supplements and fortified food in German children and adolescents: results from the DONALD study. J Nutr 2006; 136:1329–1333.
Domellof M, Szitanyi P, Simchowitz V, et al. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: iron and trace minerals. Clin Nutr 2018; 37:2354–2359.
Hardy G, Wong T, Morrissey H, et al. Parenteral provision of micronutrients to pediatric patients: an international Expert Consensus Paper. JPEN J Parenter Enteral Nutr 2020; 44: (Suppl 2): S5–S23.
Berger MM, Shenkin A, Schweinlin A, et al. ESPEN micronutrient guideline. Clin Nutr 2022; 41:1357–1424.
UNICEF-Uganda. Key practice: Micronutrients for children, adolescents and women - why they are important for your family. https://www.unicef.org/uganda/key-practice-micronutrients-children-adolescents-and-women. 2024.
Suthutvoravut U, Abiodun PO, Chomtho S, et al. Composition of follow-up formula for young children aged 12-36 months: recommendations of an International Expert Group Coordinated by the Nutrition Association of Thailand and the Early Nutrition Academy. Ann Nutr Metab 2015; 67:119–132.
Tam E, Keats EC, Rind F, et al. Micronutrient supplementation and fortification interventions on health and development outcomes among children under-five in low- and middle-income countries: a systematic review and meta-analysis. Nutrients 2020; 12:289.
Allen LH. Zinc and micronutrient supplements for children. Am J Clin Nutr 1998; 68:495S–498S.
Doom JR, Richards B, Caballero G, et al. Infant iron deficiency and iron supplementation predict adolescent internalizing, externalizing, and social problems. J Pediatr 2018; 195:199–205.
Trapani S, Rubino C, Indolfi G, Lionetti P. A narrative review on pediatric scurvy: the last twenty years. Nutrients 2022; 14:684.
Hargreaves D, Mates E, Menon P, et al. Strategies and interventions for healthy adolescent growth, nutrition, and development. Lancet 2022; 399:198–210.
Chao HC, Lu JJ, Yang CY, et al. Serum trace element levels and their correlation with picky eating behavior, development, and physical activity in early childhood. Nutrients 2021; 13:2295.
Kuriyan R, Thankachan P, Selvam S, et al. The effects of regular consumption of a multiple micronutrient fortified milk beverage on the micronutrient status of school children and on their mental and physical performance. Clin Nutr 2016; 35:190–198.
Nawab F, Fatima S, Nazli R, et al. Micronutrient status and energy intake in moderate acute malnourished children after intake of high energy nutritional supplements for four weeks: a randomized controlled study. J Ayub Med Coll Abbottabad 2022; 34:239–246.
Ning Y, Hu M, Chen S, et al. Investigation of selenium nutritional status and dietary pattern among children in Kashin-Beck disease endemic areas in Shaanxi Province, China using duplicate portion sampling method. Environ Int 2022; 164:107255.
Chouraqui JP. Risk assessment of micronutrients deficiency in vegetarian or vegan children: not so obvious. Nutrients 2023; 15:2129.
Svetnicka M, Henikova M, Selinger E, et al. Prevalence of iodine deficiency among vegan compared to vegetarian and omnivore children in the Czech Republic: cross-sectional study. Eur J Clin Nutr 2023; 77:1061–1070.
Svetnicka M, Sigal A, Selinger E, et al. Cross-sectional study of the prevalence of cobalamin deficiency and Vitamin B12 supplementation habits among vegetarian and vegan children in the Czech Republic. Nutrients 2022; 14:535.
Lemale J, Mas E, Jung C, et al. Vegan diet in children and adolescents. Recommendations from the French-speaking Pediatric Hepatology, Gastroenterology and Nutrition Group (GFHGNP). Arch Pediatr 2019; 26:442–450.
Stevens GA, Finucane MM, De-Regil LM, et al. Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and nonpregnant women for 1995-2011: a systematic analysis of population-representative data. Lancet Glob Health 2013; 1:e16–e25.
Yusufu I, Cliffer IR, Yussuf MH, et al. Factors associated with anemia among school-going adolescents aged 10-17 years in Zanzibar, Tanzania: a cross sectional study. BMC Public Health 2023; 23:1814.
Handiso YH, Belachew T, Abuye C, et al. A community-based randomized controlled trial providing weekly iron-folic acid supplementation increased serum- ferritin, -folate and hemoglobin concentration of adolescent girls in southern Ethiopia. Sci Rep 2021; 11:9646.
Gupta A, Kant S, Ramakrishnan L, et al. Impact of daily-supervised administration of a package of iron and folic acid and vitamin B(12) on hemoglobin levels among adolescent girls (12-19 years): a cluster randomized control trial. Eur J Clin Nutr 2021; 75:1588–1597.
Hoang NTD, Orellana L, Gibson RS, et al. Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial. Sci Rep 2021; 11:3728.
Tandon R, Thacker J, Pandya U, et al. Parenteral vs oral Vitamin B12 in children with nutritional macrocytic anemia: a randomized controlled trial. Indian Pediatr 2022; 59:683–687.
Black MM, Fernandez-Rao S, Nair KM, et al. A randomized multiple micronutrient powder point-of-use fortification trial implemented in Indian preschools increases expressive language and reduces anemia and iron deficiency. J Nutr 2021; 151:2029–2042.
Bassouni R, Soliman M, Hussein LA, et al. Development and evaluating the biopotency of ready to eat liver meat balls in fighting anaemia and vitamin A deficiency, improving selected nutritional biochemical indicators and promoting the cognitive function among mildly anaemic Egyptian children aged 3-9 years. Public Health Nutr 2022; 25:3182–3194.
Berglund SK, Domellof M. Iron deficiency in infancy: current insights. Curr Opin Clin Nutr Metab Care 2021; 24:240–245.
Aslan N. A case of iron intoxication treated by plasmapheresis. Indian J Pediatr 2022; 89:315.
Ganmaa D, Bromage S, Khudyakov P, et al. Influence of Vitamin D supplementation on growth, body composition, and pubertal development among school-aged children in an area with a high prevalence of Vitamin D deficiency: a randomized clinical trial. JAMA Pediatr 2023; 177:32–41.
Tamara L, Kartasasmita CB, Alam A, Gurnida DA. Effects of Vitamin D supplementation on resolution of fever and cough in children with pulmonary tuberculosis: a randomized double-blind controlled trial in Indonesia. J Glob Health 2022; 12:04015.
Forno E, Bacharier LB, Phipatanakul W, et al. Effect of Vitamin D3 supplementation on severe asthma exacerbations in children with asthma and low Vitamin D levels: the VDKA randomized clinical trial. JAMA 2020; 324:752–760.
Reinehr T, Schnabel D, Wabitsch M, et al. Vitamin D supplementation after the second year of life: joint position of the Committee on Nutrition, German Society for Pediatric and Adolescent Medicine (DGKJ e.V.), and the German Society for Pediatric Endocrinology and Diabetology (DGKED e.V.). Mol Cell Pediatr 2019; 6:3.
Braegger C, Campoy C, Colomb V, et al. Vitamin D in the healthy European paediatric population. J Pediatr Gastroenterol Nutr 2013; 56:692–701.
Onal S, Sachadyn-Krol M, Kostecka M. A review of the nutritional approach and the role of dietary components in children with autism spectrum disorders in light of the latest scientific research. Nutrients 2023; 15:4852.
Adams JB, Kirby J, Audhya T, et al. Vitamin/mineral/micronutrient supplement for autism spectrum disorders: a research survey. BMC Pediatr 2022; 22:590.
Saati AA, Adly HM. Assessing the correlation between blood trace element concentrations, picky eating habits, and intelligence quotient in school-aged children. Children (Basel) 2023; 10:1249.
Pongpitakdamrong A, Chirdkiatgumchai V, Ruangdaraganon N, et al. Effect of iron supplementation in children with attention-deficit/hyperactivity disorder and iron deficiency: a randomized controlled trial. J Dev Behav Pediatr 2022; 43:80–86.
Hemamy M, Pahlavani N, Amanollahi A, et al. The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial. BMC Pediatr 2021; 21:178.
German Consumer Organisation. Food supplements for children - market check of the consumer centres. https://www.verbraucherzentrale.de. 2019. pp. https://www.klartext-nahrungsergaenzung.de/sites/default/files/2019-08/MarktcheckNEM-fuer-Kinder-BMEL_Englisch-2019.pdf.
Bailey RL, Fulgoni VL 3rd, Keast DR, et al. Do dietary supplements improve micronutrient sufficiency in children and adolescents? J Pediatr 2012; 161:837–842.
Pike V, Zlotkin S. Excess micronutrient intake: defining toxic effects and upper limits in vulnerable populations. Ann N Y Acad Sci 2019; 1446:21–43.