Investigating the Association Between Extended Participation in Collision Sports and Fluid Biomarkers Among Masters Athletes.
GFAP
NfL
UCH-L1
concussion
inflammation
neurodegeneration
p-tau-181
tau
telomere
Journal
Neurotrauma reports
ISSN: 2689-288X
Titre abrégé: Neurotrauma Rep
Pays: United States
ID NLM: 101773091
Informations de publication
Date de publication:
2024
2024
Historique:
medline:
11
3
2024
pubmed:
11
3
2024
entrez:
11
3
2024
Statut:
epublish
Résumé
Traumatic brain injuries (TBIs) and concussions are prevalent in collision sports, and there is evidence that levels of exposure to such sports may increase the risk of neurological abnormalities. Elevated levels of fluid-based biomarkers have been observed after concussions or among athletes with a history of participating in collision sports, and certain biomarkers exhibit sensitivity toward neurodegeneration. This study investigated a cohort of 28 male amateur athletes competing in "Masters" competitions for persons >35 years of age. The primary objective of this study was to compare the levels of blood and saliva biomarkers associated with brain injury, inflammation, aging, and neurodegeneration between athletes with an extensive history of collision sport participation (i.e., median = 27 years; interquartile range = 18-44, minimum = 8) and those with no history. Plasma proteins associated with neural damage and neurodegeneration were measured using Simoa
Identifiants
pubmed: 38463419
doi: 10.1089/neur.2023.0086
pii: 10.1089/neur.2023.0086
pmc: PMC10923547
doi:
Types de publication
Journal Article
Langues
eng
Pagination
74-80Informations de copyright
© Lauren P. Giesler et al., 2024; Published by Mary Ann Liebert, Inc.
Déclaration de conflit d'intérêts
No competing financial interests exist.