TUBA4A downregulation as observed in ALS

TUBA4A amyotrophic lateral sclerosis axonal pathology microtubules zebrafish

Journal

Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935

Informations de publication

Date de publication:
2024
Historique:
received: 17 11 2023
accepted: 22 01 2024
medline: 11 3 2024
pubmed: 11 3 2024
entrez: 11 3 2024
Statut: epublish

Résumé

Disease-associated variants of

Identifiants

pubmed: 38463699
doi: 10.3389/fncel.2024.1340240
pmc: PMC10921936
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1340240

Informations de copyright

Copyright © 2024 Van Schoor, Strubbe, Braems, Weishaupt, Ludolph, Van Damme, Thal, Bercier and Van Den Bosch.

Déclaration de conflit d'intérêts

ACL serves on the Advisory Board of Roche Pharma (Basel, Switserland) and Biogen (Cambridge, MA, USA), and on the data and safety monitoring board of Zeneus pharma (Bray, UK). ACL received consulting fees from AB Science (Paris, France), Desitin (Buckinghamshire, UK), Novartis (Basel, Switserland) and Teva (Jerusalem, Israel). PVD participated in advisory board meetings of Biogen (Cambridge, MA, USA), Cytokinetics (San Francisco, CA, USA), Ferrer (Barcelona, Spain), UCB (Brussels, Belgium), Argenx (Ghent, Belgium), Muna Therapeutics (Copenhagen, Denmark), Alector (San Francisco, CA, USA), Augustine Therapeutics (Leuven, Belgium), Alexion Therapeutics (Boston, MA, USA) and QurAlis (Cambridge, MA, USA). DRT received speaker honorary or travel reimbursement from Biogen (USA), UCB (Brussels, Belgium), and collaborated with Novartis Pharma AG (Basel, Switzerland), Probiodrug [Halle (Saale), Germany, GE Healthcare Amersham, UK], and Janssen Pharmaceutical Companies (Beerse, Belgium). LVDB is scientific founder and head of the Scientific Advisory Board of Augustine Therapeutics (Leuven, Belgium). The funders had no role in the design of the study; in the collection, analyses or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Auteurs

Evelien Van Schoor (E)

Laboratory of Neuropathology, Department of Imaging and Pathology, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Laboratory of Neurobiology, Department of Neurosciences, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Center for Brain and Disease Research, VIB, Leuven, Belgium.

Dufie Strubbe (D)

Laboratory of Neurobiology, Department of Neurosciences, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Center for Brain and Disease Research, VIB, Leuven, Belgium.

Elke Braems (E)

Laboratory of Neurobiology, Department of Neurosciences, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Center for Brain and Disease Research, VIB, Leuven, Belgium.

Jochen Weishaupt (J)

Department of Neurology, Ulm University, Ulm, Germany.

Albert C Ludolph (AC)

Department of Neurology, Ulm University, Ulm, Germany.
Deutsches Zentrum für Neurodegenerative Erkrankungen, Ulm, Germany.

Philip Van Damme (P)

Laboratory of Neurobiology, Department of Neurosciences, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Center for Brain and Disease Research, VIB, Leuven, Belgium.
Department of Neurology, University Hospitals Leuven, Leuven, Belgium.

Dietmar Rudolf Thal (DR)

Laboratory of Neuropathology, Department of Imaging and Pathology, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Department of Pathology, University Hospitals Leuven, Leuven, Belgium.

Valérie Bercier (V)

Laboratory of Neurobiology, Department of Neurosciences, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Center for Brain and Disease Research, VIB, Leuven, Belgium.

Ludo Van Den Bosch (L)

Laboratory of Neurobiology, Department of Neurosciences, KU Leuven (University of Leuven) and Leuven Brain Institute (LBI), Leuven, Belgium.
Center for Brain and Disease Research, VIB, Leuven, Belgium.

Classifications MeSH