Potent small molecule inhibitors against the 3C protease of foot-and-mouth disease virus.

3C protease antiviral food-and-mouth disease protease inhibitor structure-activity relationships

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
11 Mar 2024
Historique:
medline: 11 3 2024
pubmed: 11 3 2024
entrez: 11 3 2024
Statut: aheadofprint

Résumé

Foot-and-mouth disease (FMD) is one of the most devastating diseases of livestock which can cause significant economic losses, especially when introduced to FMD-free countries. FMD virus (FMDV) belongs to the family

Identifiants

pubmed: 38466127
doi: 10.1128/spectrum.03372-23
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0337223

Auteurs

Yunjeong Kim (Y)

Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA.

Emma Pool (E)

Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA.

Eunji Kim (E)

Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA.

Chamandi S Dampalla (CS)

Department of Chemistry, Wichita State University, Wichita, Kansas, USA.

Harry Nhat Nguyen (HN)

Department of Chemistry, Wichita State University, Wichita, Kansas, USA.

David K Johnson (DK)

Computational Chemical Biology Core, The University of Kansas, Lawrence, Kansas, USA.

Scott Lovell (S)

Protein Structure and X-ray Crystallography Laboratory, The University of Kansas, Lawrence, Kansas, USA.

William C Groutas (WC)

Department of Chemistry, Wichita State University, Wichita, Kansas, USA.

Kyeong-Ok Chang (K-O)

Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA.

Classifications MeSH