NG2 Molecule Expression in Acute Lymphoblastic Leukemia B Cells: A Flow-Cytometric Marker for the Rapid Identification of
Acute lymphoblastic leukemia
Flow-cytometry
KMT2A gene rearrangements
NG2
Journal
Mediterranean journal of hematology and infectious diseases
ISSN: 2035-3006
Titre abrégé: Mediterr J Hematol Infect Dis
Pays: Italy
ID NLM: 101530512
Informations de publication
Date de publication:
2024
2024
Historique:
received:
17
10
2023
accepted:
08
02
2024
medline:
12
3
2024
pubmed:
12
3
2024
entrez:
12
3
2024
Statut:
epublish
Résumé
B-lineage acute lymphoblastic leukemias (B-ALL) harboring rearrangements of the histone lysine [K]-Methyltransferase 2A ( We evaluated 88 NG2+ B-ALL cases identified with an NG2 positivity threshold >10% from a cohort of 1382 newly diagnosed B-ALLs referred to the Division of Hematology of 'Sapienza' University of Rome. Eighty-five of 88 (96.6%) NG2+ B-ALLs harbored Our data demonstrate the association between NG2 and
Sections du résumé
Background
UNASSIGNED
B-lineage acute lymphoblastic leukemias (B-ALL) harboring rearrangements of the histone lysine [K]-Methyltransferase 2A (
Materials and Methods
UNASSIGNED
We evaluated 88 NG2+ B-ALL cases identified with an NG2 positivity threshold >10% from a cohort of 1382 newly diagnosed B-ALLs referred to the Division of Hematology of 'Sapienza' University of Rome.
Results
UNASSIGNED
Eighty-five of 88 (96.6%) NG2+ B-ALLs harbored
Conclusions
UNASSIGNED
Our data demonstrate the association between NG2 and
Identifiants
pubmed: 38468826
doi: 10.4084/MJHID.2024.018
pii: mjhid-16-1-e2024018
pmc: PMC10927233
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e2024018Déclaration de conflit d'intérêts
Competing interests: The authors declare no conflict of Interest.