Ovarian mass in a patient with invasive breast carcinoma: A case report of an unexpected diagnosis.

Breast carcinoma Ovarian steroid cell tumor Ovarian tumor Sex cord tumor

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
04 Mar 2024
Historique:
received: 27 12 2023
revised: 23 02 2024
accepted: 27 02 2024
medline: 13 3 2024
pubmed: 13 3 2024
entrez: 12 3 2024
Statut: aheadofprint

Résumé

Ovarian steroid cell tumors not otherwise specified (OSCT-NOS) are extremely rare ovarian sex cord stromal tumors, accounting for <0.1 % of all ovarian tumors. In 25 % of cases, they are asymptomatic leading to a delay in diagnosis. We, herein, report a singular case of OSCT-NOS diagnosed incidentally during the spread assessment of an invasive breast carcinoma of no special type (IBC-NOS). To the best of our knowledge, this is the first reported case of co-occurrence of OSCT-NOS and IBC-NOS. We aim to study the clinic-pathological characteristics of this rare tumor. A 56-years old postmenopausal female, with no previous medical history, was diagnosed with an invasive IBC-NOS. The tomography performed during the spread assessment of IBC-NOS showed a suspicious mass of the right ovary. Pelvic MRI revealed an ovarian solid T1 isointense and T2 hyperintense mass. The first evoked diagnosis was an ovarian metastasis of the IBC-NOS. The patient underwent bilateral salpingo-oophorectomy. On gross examination, an ovarian solid mass measuring 2,5x2cm, with a firm gray yellowish cut surface was noted. Microscopic examination and immunostaining concluded to OSCT-NOS and ruled out the diagnosis of an ovarian metastasis of IBC-NOS. OSCT-NOS are rare neoplasms. Their diagnosis might be challenging especially in absence of hormonal symptoms. A better knowledge of this rare entities would enable early diagnosis.

Identifiants

pubmed: 38471218
pii: S2210-2612(24)00238-4
doi: 10.1016/j.ijscr.2024.109457
pmc: PMC10945163
pii:
doi:

Types de publication

Case Reports

Langues

eng

Pagination

109457

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest We declare no conflict of interest.

Références

CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
Int J Surg. 2023 May 01;109(5):1136-1140
pubmed: 37013953
BMC Endocr Disord. 2022 Nov 1;22(1):265
pubmed: 36316664
Yonsei Med J. 2007 Feb 28;48(1):142-6
pubmed: 17326260
BMC Cancer. 2022 Sep 26;22(1):1018
pubmed: 36163009
J Assist Reprod Genet. 2013 Sep;30(9):1157-60
pubmed: 23868533
J Med Case Rep. 2022 Dec 24;16(1):478
pubmed: 36564842
Am J Surg Pathol. 1987 Nov;11(11):835-45
pubmed: 2823622
BMC Womens Health. 2021 Mar 4;21(1):95
pubmed: 33663470
Int J Gynecol Cancer. 2023 Oct 2;33(10):1660-1662
pubmed: 37419514
Fukushima J Med Sci. 2020 Jan 9;65(3):133-139
pubmed: 31827013
J Midlife Health. 2021 Jan-Mar;12(1):82-84
pubmed: 34188431
Diagnosis (Berl). 2018 Jun 27;5(2):83-87
pubmed: 29752879
Fetal Pediatr Pathol. 2011;30(1):16-21
pubmed: 21204661
Medicine (Baltimore). 2017 Sep;96(37):e7998
pubmed: 28906379

Auteurs

Maissa Ben Thayer (MB)

Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia; Salah Azaïez's Institute, Department of Pathology, Tunis, Tunisia. Electronic address: benthayerm@hotmail.com.

Ghada Sahraoui (G)

Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia; Salah Azaïez's Institute, Department of Pathology, Tunis, Tunisia.

Hassine Saber Abouda (HS)

C Unit, Tunis Maternity and Neonatology Center, Tunis, Tunisia.

Mahdi Farhati (M)

C Unit, Tunis Maternity and Neonatology Center, Tunis, Tunisia.

Raoudha Doghri (R)

Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia; Salah Azaïez's Institute, Department of Pathology, Tunis, Tunisia.

Karima Mrad (K)

Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia; Salah Azaïez's Institute, Department of Pathology, Tunis, Tunisia.

Classifications MeSH