Practical and methodological challenges when conducting a cluster randomized trial: Examples and recommendations.
Challenges
Cluster randomized trial
Cross-over
Design
Implementation
Methodological recommendations
Stepped-wedge
Journal
Journal of epidemiology and population health
ISSN: 2950-4333
Titre abrégé: J Epidemiol Popul Health
Pays: France
ID NLM: 9918769574106676
Informations de publication
Date de publication:
Feb 2024
Feb 2024
Historique:
received:
27
10
2023
revised:
19
01
2024
accepted:
19
01
2024
medline:
13
3
2024
pubmed:
13
3
2024
entrez:
13
3
2024
Statut:
ppublish
Résumé
The use of cluster randomized trial design to answer research questions is increasing. This design and associated variants such as the cluster randomized crossover and stepped wedge are useful to assess complex interventions in a pragmatic way but when adopting such designs, one may face specific implementation challenges. This article summarizes common challenges faced when conducting cluster randomized trials, cluster randomized crossover trials, and stepped wedge trials, and provides recommendations.
Identifiants
pubmed: 38477480
pii: S2950-4333(24)00010-7
doi: 10.1016/j.jeph.2024.202199
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
202199Informations de copyright
Copyright © 2024 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare they have no competing interests.