Textbook outcome in patients with biliary duct injury during cholecystectomy.

Bile duct injury Morbidity Outcomes

Journal

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
ISSN: 1873-4626
Titre abrégé: J Gastrointest Surg
Pays: Netherlands
ID NLM: 9706084

Informations de publication

Date de publication:
21 Feb 2024
Historique:
received: 08 01 2024
revised: 11 02 2024
accepted: 17 02 2024
medline: 14 3 2024
pubmed: 14 3 2024
entrez: 13 3 2024
Statut: aheadofprint

Résumé

Iatrogenic bile duct injury (BDI) during cholecystectomy is associated with a complex and heterogeneous management owing to the burden of morbidity until their definitive treatment. This study aimed to define the textbook outcomes (TOs) after BDI with the purpose to indicate the ideal treatment and to improve it management. We collected data from patients with an BDI between 1990 and 2022 from 27 hospitals. TO was defined as a successful conservative treatment of the iatrogenic BDI or only minor complications after BDI or patients in whom the first repair resolves the iatrogenic BDI without complications or with minor complications. We included 808 patients and a total of 394 patients (46.9%) achieved TO. Overall complications in TO and non-TO groups were 11.9% and 86%, respectively (P < .001). Major complications and mortality in the non-TO group were 57.4% and 9.2%, respectively. The use of end-to-end bile duct anastomosis repair was higher in the non-TO group (23.1 vs 7.8, P < .001). Factors associated with achieving a TO were injury in a specialized center (adjusted odds ratio [aOR], 4.01; 95% CI, 2.68-5.99; P < .001), transfer for a first repair (aOR, 5.72; 95% CI, 3.51-9.34; P < .001), conservative management (aOR, 5.00; 95% CI, 1.63-15.36; P = .005), or surgical management (aOR, 2.45; 95% CI, 1.50-4.00; P < .001). TO largely depends on where the BDI is managed and the type of injury. It allows hepatobiliary centers to identify domains of improvement of perioperative management of patients with BDI.

Sections du résumé

BACKGROUND BACKGROUND
Iatrogenic bile duct injury (BDI) during cholecystectomy is associated with a complex and heterogeneous management owing to the burden of morbidity until their definitive treatment. This study aimed to define the textbook outcomes (TOs) after BDI with the purpose to indicate the ideal treatment and to improve it management.
METHODS METHODS
We collected data from patients with an BDI between 1990 and 2022 from 27 hospitals. TO was defined as a successful conservative treatment of the iatrogenic BDI or only minor complications after BDI or patients in whom the first repair resolves the iatrogenic BDI without complications or with minor complications.
RESULTS RESULTS
We included 808 patients and a total of 394 patients (46.9%) achieved TO. Overall complications in TO and non-TO groups were 11.9% and 86%, respectively (P < .001). Major complications and mortality in the non-TO group were 57.4% and 9.2%, respectively. The use of end-to-end bile duct anastomosis repair was higher in the non-TO group (23.1 vs 7.8, P < .001). Factors associated with achieving a TO were injury in a specialized center (adjusted odds ratio [aOR], 4.01; 95% CI, 2.68-5.99; P < .001), transfer for a first repair (aOR, 5.72; 95% CI, 3.51-9.34; P < .001), conservative management (aOR, 5.00; 95% CI, 1.63-15.36; P = .005), or surgical management (aOR, 2.45; 95% CI, 1.50-4.00; P < .001).
CONCLUSION CONCLUSIONS
TO largely depends on where the BDI is managed and the type of injury. It allows hepatobiliary centers to identify domains of improvement of perioperative management of patients with BDI.

Identifiants

pubmed: 38480039
pii: S1091-255X(24)00334-2
doi: 10.1016/j.gassur.2024.02.027
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Auteurs

Victor Lopez-Lopez (V)

Department of Surgery and Transplantation, Virgen de la Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Murcia, Spain. Electronic address: victorrelopez@gmail.com.

Christoph Kuemmerli (C)

Department of Surgery, Clarunis University Center for Gastrointestinal and Liver Diseases, Basel, Switzerland.

Javier Maupoey (J)

Department of Hepatobiliary Surgery and Transplants, Hospital Universitario La Fe, Valencia, Spain.

Rafael López-Andujar (R)

Department of Hepatobiliary Surgery and Transplants, Hospital Universitario La Fe, Valencia, Spain.

Laura Lladó (L)

Department of Hepatobiliary Surgery and Liver Transplant Unit, Hospital Universitari Bellvitge, University of Barcelona, Barcelona, Spain.

Kristel Mils (K)

Department of Hepatobiliary Surgery and Liver Transplant Unit, Hospital Universitari Bellvitge, University of Barcelona, Barcelona, Spain.

Philip Müller (P)

Department of Surgery, Clarunis University Center for Gastrointestinal and Liver Diseases, Basel, Switzerland; Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.

Andres Valdivieso (A)

Hepatobiliary Surgery and Liver Transplant Unit, Cruces University Hospital, Bilbao, Spain.

Marina Garcés-Albir (M)

Department of Surgery, Hospital Clínico, University of Valencia, Biomedical Research Institute INCLIVA, Valencia, Spain.

Luis Sabater (L)

Department of Surgery, Hospital Clínico, University of Valencia, Biomedical Research Institute INCLIVA, Valencia, Spain.

Andrea Benedetti Cacciaguerra (AB)

Department of Experimental and Clinical Medicine, Hepatobiliary and Abdominal Transplantation Surgery, Riuniti Hospital, Polytechnic University of Marche, Ancona, Italy.

Marco Vivarelli (M)

Department of Experimental and Clinical Medicine, Hepatobiliary and Abdominal Transplantation Surgery, Riuniti Hospital, Polytechnic University of Marche, Ancona, Italy.

Luis Díez Valladares (LD)

Department of Surgery, Hepatopancreatobiliary Unit, Hospital Clínico San Carlos, Madrid, Spain.

Sergio Annese Pérez (SA)

Department of Surgery, Morales University Hospital, Madrid, Spain.

Benito Flores (B)

Department of Surgery, Morales University Hospital, Madrid, Spain.

Roberto Brusadin (R)

Department of Surgery and Transplantation, Virgen de la Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Murcia, Spain.

Asunción López Conesa (AL)

Department of Surgery and Transplantation, Virgen de la Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Murcia, Spain.

Sagrario Martinez Cortijo (SM)

Department of Surgery, Alcorcon University Hospital, Madrid, Spain.

Sandra Paterna (S)

Department of Surgery, Miguel Servet University Hospital, Zaragoza, Spain.

Alejando Serrablo (A)

Department of Surgery, Miguel Servet University Hospital, Zaragoza, Spain.

Ferdinand Heinz Walther Toop (FHW)

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Asklepios Hospital Barmbek, Germany.

Karl Oldhafer (K)

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Asklepios Hospital Barmbek, Germany.

Santiago Sánchez-Cabús (S)

Hepatobiliopancreatic Surgery Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

Antonio González Gil (AG)

Department of Surgery, Los Arcos del Mar Menor University Hospital, Murcia, Spain.

Jose Antonio González Masía (JAG)

Department of Surgery, General University Hospital, Albacete, Spain.

Carmelo Loinaz (C)

Department of General Surgery, Digestive Tract and Abdominal Organ Transplantation, Hospital Universitario, 12 de Octubre, Madrid, Spain.

Jose Luis Lucena (JL)

Department of Surgery, Puerta del Hierro University Hospital, Madrid, Spain.

Patricia Pastor (P)

Department of Surgery, Reina Sofía University Hospital, Murcia, Spain.

Cristina Garcia-Zamora (C)

Department of Surgery, Rafael Mendez Hospital, Murcia, Spain.

Alicia Calero (A)

Department of General Surgery, Elche University Hospital, University Miguel Hernández of Elche, Alicante, Spain.

Juan Valiente (J)

Department of General Surgery, Hellin Hospital, Albacete, Spain.

Antonio Minguillon (A)

Department of General Surgery, Obispo Polanco Hospital, Teruel, Spain.

Fernando Rotellar (F)

Institute of Health Research of Navarra (IDISNA), Pamplona, Spain; HPB and Liver Transplant Unit, Abdominal and General Surgery, Clinica Universidad de Navarra, Pamplona, Spain.

Cándido Alcazar (C)

Department of Surgery, University Hospital of Alicante, and Universidad Miguel Hernandez, ISABIAL, Alicante, Spain.

Javier Aguilo (J)

Department of General Surgery, Hospital Lluís Alcanyís Hospital, Xàtiva, Valencia, Spain.

Jose Cutillas (J)

Department of General Surgery, Hospital Francesc de Borja, Gandía, Valencia, Spain.

Jose A Ruiperez-Valiente (JA)

Department of Information and Communication Engineering, Universidad de Murcia, Spain.

Pablo Ramírez (P)

Department of Surgery and Transplantation, Virgen de la Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Murcia, Spain.

Henrik Petrowsky (H)

Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.

Jose Manuel Ramia (JM)

Department of Surgery, University Hospital of Alicante, and Universidad Miguel Hernandez, ISABIAL, Alicante, Spain.

Ricardo Robles-Campos (R)

Department of Surgery and Transplantation, Virgen de la Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Murcia, Spain.

Classifications MeSH