[Pediatric aphereses (workshop SFGM-TC)].

Cytaphérèses pédiatriques (atelier SFGM-TC).
Apheresis Atelier d’harmonisation Cytaphérèse Greffe de cellules souches hématopoïétiques Guidelines Hematopoietic cell transplantation Pediatrics Practice harmonization workshop Pédiatrie Recommandations SFGM-TC

Journal

Bulletin du cancer
ISSN: 1769-6917
Titre abrégé: Bull Cancer
Pays: France
ID NLM: 0072416

Informations de publication

Date de publication:
12 Mar 2024
Historique:
received: 07 11 2023
revised: 28 11 2023
accepted: 06 12 2023
medline: 14 3 2024
pubmed: 14 3 2024
entrez: 13 3 2024
Statut: aheadofprint

Résumé

Practice of pediatric aphereses - in particular when caring for low-weight children - differs from the practice of adult aphereses, since pediatric aphereses represent low numbers of procedures, which has practical implications in terms of practical training and retraining for involved healthcare personnel, as needed for habilitation and validation of ongoing competencies. A specific training is mandatory in order to ensure both the child and the staff safety during and after collection, as well as ensure high quality of the collected cell product and that its meets predefined specifications that depend on its intended use. Low and very low-weight children deserve a particular attention for a number of procedural and clinical aspects: the nature and quality of venous accesses to ensure proper operation of the cell separator, management of hemodynamic fluctuations in relation with the relative importance of the extracorporeal blood volume as compared to the total blood volume of the child, risks and clinical manifestations of citrate toxicity, minimization of stress during the procedure that may include but is not limited to pharmacological sedation. The full spectrum of competencies needed to deal with these aspects is rarely present within a single team of healthcare professionals; it most often requires the tight combination of expertise drawing from the collection facility, the pediatric department and possibly the pediatric intensive care unit ward, whether from the same or from different institutions. Interactions must be formalized in a document that accurately describes which category of actors is responsible for each category of acts (prescriptions, decisions), depending on their initial qualifications, specific competencies, and affiliations.

Identifiants

pubmed: 38480055
pii: S0007-4551(24)00042-0
doi: 10.1016/j.bulcan.2023.12.008
pii:
doi:

Types de publication

English Abstract Practice Guideline

Langues

fre

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

Christian Chabannon (C)

Inserm CBT-1409 module biothérapies du centre d'investigations cliniques en biothérapies de Marseille, centre de thérapie cellulaire, institut Paoli-Calmettes, Aix-Marseille université, Marseille, France. Electronic address: chabannonc@ipc.unicancer.fr.

Malek Benakli (M)

Centre Pierre et Marie Curie, Algers, Algérie.

Kamelia Alexandrova (K)

Institut Gustave-Roussy, Villejuif, France.

Carole Coze (C)

Département d'hématologie et d'oncologie pédiatriques, hôpitaux universitaires de Marseille, Assistance publique-Hôpitaux de Marseille, Marseille, France.

Jean-Hughes Dalle (JH)

Hôpital Robert-Debré, AP-HP, Paris, France.

Christine Giraud (C)

Centre hospitalier universitaire (CHU) de Poitiers, Poitiers, France.

Phuong Huynh (P)

Institut Jules Bordet, Bruxelles, Belgique.

Tarik Kanouni (T)

Unité d'aphérèse thérapeutique et d'hémovigilance, centre hospitalier universitaire (CHU) de Montpellier, 34295 Montpellier, France; Société française d'hémaphérèse (SFH), Paris, France.

Justyna Kanold (J)

Centre hospitalier universitaire (CHU) de Clermont-Ferrand, Clermont-Ferrand, France.

Isabelle Lesieur (I)

Établissement français du sang (EFS) Hauts-de-France - Normandie, Rouen, France.

Aurélie Levavasseur (A)

Établissement français du sang (EFS) Hauts-de-France - Normandie, Rouen, France; Centre Henri-Becquerel, Rouen, France.

Ibrahim Yakoub-Agha (I)

Inserm U995, LIRIC, université de Lille, CHU de Lille, 59000 Lille, France.

Etienne Baudoux (E)

Centre hospitalier universitaire (CHU) de Liège, Liège, Belgique.

Classifications MeSH