Blood lead levels in pregnant women and their newborn infants at an Indian teaching hospital.

Blood lead level DNA damage comet assay lead poisoning newborn reproductive toxicity

Journal

Journal of family medicine and primary care
ISSN: 2249-4863
Titre abrégé: J Family Med Prim Care
Pays: India
ID NLM: 101610082

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 12 06 2023
revised: 05 07 2023
accepted: 06 10 2023
medline: 14 3 2024
pubmed: 14 3 2024
entrez: 14 3 2024
Statut: ppublish

Résumé

With the growth of the world's economy and industrialization, lead (Pb) contamination in the environment has become a major issue on a global scale. Lead is typically linked to unfavorable pregnancy outcomes such as stillbirth, low birth weight preterm, and spontaneous abortion. In this study, we evaluated the blood lead levels of pregnant women and their birth outcomes attending an Indian tertiary care teaching hospital, those who were not exposed to any lead-associated industry or shops. A descriptive study was undertaken to evaluate blood lead estimation in pregnant women and umbilical blood lead levels in a community hospital. Blood samples from 104 mothers during the 1 Among 194 blood samples of pregnant women, 31 (15.98%) samples revealed ≥5 μg/dL blood lead levels. High lead concentration (≥5 µg/dL) in 1 In this descriptive study, there was a significant amount of lead transferred from mother to baby through the placenta. All mothers were not exposed to lead-associated industry and most were housewives. This article may be viewed as an eye-opener for understanding the blood lead concentration during pregnancy to avoid abnormal birth outcomes. To minimize exposure to environmental lead, all possible measures should be undertaken.

Sections du résumé

Background and Aim UNASSIGNED
With the growth of the world's economy and industrialization, lead (Pb) contamination in the environment has become a major issue on a global scale. Lead is typically linked to unfavorable pregnancy outcomes such as stillbirth, low birth weight preterm, and spontaneous abortion. In this study, we evaluated the blood lead levels of pregnant women and their birth outcomes attending an Indian tertiary care teaching hospital, those who were not exposed to any lead-associated industry or shops.
Methods UNASSIGNED
A descriptive study was undertaken to evaluate blood lead estimation in pregnant women and umbilical blood lead levels in a community hospital. Blood samples from 104 mothers during the 1
Results UNASSIGNED
Among 194 blood samples of pregnant women, 31 (15.98%) samples revealed ≥5 μg/dL blood lead levels. High lead concentration (≥5 µg/dL) in 1
Conclusion UNASSIGNED
In this descriptive study, there was a significant amount of lead transferred from mother to baby through the placenta. All mothers were not exposed to lead-associated industry and most were housewives. This article may be viewed as an eye-opener for understanding the blood lead concentration during pregnancy to avoid abnormal birth outcomes. To minimize exposure to environmental lead, all possible measures should be undertaken.

Identifiants

pubmed: 38482293
doi: 10.4103/jfmpc.jfmpc_963_23
pii: JFMPC-13-348
pmc: PMC10931910
doi:

Types de publication

Journal Article

Langues

eng

Pagination

348-355

Informations de copyright

Copyright: © 2024 Journal of Family Medicine and Primary Care.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Auteurs

Mahesh C Sahu (MC)

ICMR-Regional Medical Research Centre, Chandrasekharpur, Bhubaneswar, Odisha, India.

Mehta R Yogeshbhai (MR)

Department of Gynaecology and Obstetrics, Civil Hospital, Meghaninagar, Ahmedabad, Gujarat, India.

Hina Oza (H)

Department of Gynaecology and Obstetrics, Civil Hospital, Meghaninagar, Ahmedabad, Gujarat, India.

Kuldip Upadhyay (K)

Division of Occupational Hygiene, ICMR-National Institute of Occupational Health, Meghaninagar, Ahmedabad, Gujarat, India.

Kabita Chanania (K)

Department of Gynaecology and Obstetrics, IMS and SUM Hospital, Siksha 'O' Anusandhan University, Kalinga Nagar, Bhubaneswar, Odisha, India.

Sanghamitra Pati (S)

ICMR-Regional Medical Research Centre, Chandrasekharpur, Bhubaneswar, Odisha, India.

Classifications MeSH