Extracorporeal cardio-pulmonary resuscitation in a patient with missed diagnosis of sodium nitrite intoxication.

cardiac arrest extracorporeal cardiopulmonary resuscitation extracorporeal membrane oxygenation poisoning sodium nitrite venoarterial extracorporeal membrane oxygenation

Journal

Perfusion
ISSN: 1477-111X
Titre abrégé: Perfusion
Pays: England
ID NLM: 8700166

Informations de publication

Date de publication:
14 Mar 2024
Historique:
medline: 15 3 2024
pubmed: 15 3 2024
entrez: 15 3 2024
Statut: aheadofprint

Résumé

Critical poisoning with sodium nitrite (NaNO We report the case of an overt self-intoxication by an initially unknown agent, leading to cardiac arrest. Despite prodromal signs of cyanosis, coma, desaturation, and hypotension, methemoglobinemia went unrecognized during extracorporeal cardiopulmonary resuscitation (ECPR) as the point-of-care test failed to provide methemoglobin levels, leading to untreated methemoglobinemia. The blood flowing through the oxygenator notably maintained the same brown colour. Return of spontaneous circulation was never achieved, and the patient was declared dead after 60 min of unsuccessful resuscitation. Cause of death by means of NaNO This case highlights the risk of failure of ECPR in the context of cardiac arrest due to methemoglobinemia, emphasizing the critical need for prompt recognition of the causative agent and early administration of antidotes.

Identifiants

pubmed: 38485936
doi: 10.1177/02676591241240036
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2676591241240036

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Francesco Gaiani (F)

Department of Emergency and Intensive Care, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.

Marco Giani (M)

Department of Emergency and Intensive Care, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Beatrice Vergnano (B)

Department of Emergency and Intensive Care, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.

Jeff Sardella (J)

Service of Cardiocirculatory Physiopathology and Cardiovascular Perfusion, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.

Fabrizio Cappellini (F)

Laboratory Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Monza, Italy.

Marco Casati (M)

Laboratory Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Monza, Italy.

Matteo Pozzi (M)

Department of Emergency and Intensive Care, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Giuseppe Foti (G)

Department of Emergency and Intensive Care, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Classifications MeSH