Botulinum toxin A versus microwave thermolysis for primary axillary hyperhidrosis: A randomized controlled trial.
PROMs
QoL
RCT
botulinum toxin
bromhidrosis
hyperhidrosis
individualized treatment
microwave thermolysis
osmidrosis
personalized therapy
randomized controlled trial
Journal
JAAD international
ISSN: 2666-3287
Titre abrégé: JAAD Int
Pays: United States
ID NLM: 101774762
Informations de publication
Date de publication:
Jun 2024
Jun 2024
Historique:
accepted:
28
12
2023
medline:
18
3
2024
pubmed:
18
3
2024
entrez:
18
3
2024
Statut:
epublish
Résumé
Botulinum toxin A (BTX) and microwave thermolysis (MWT) represent 2 treatment modalities for axillary hyperhidrosis with different procedural and efficacy profiles. To compare long-term outcomes following BTX vs MWT treatment of axillary hyperhidrosis. A prospective, randomized, within-patient, controlled trial, treating axillary hyperhidrosis with contralateral BTX and MWT. Objective sweat measurement and patient-reported outcome measures for sweat and odor were collected at baseline, 6-month and 1-year follow-up (6M/1YFU). Hair reduction and patient treatment preference was also assessed. Sweat reduction was significant (all The intrinsic challenges in efficacy assessment. This study exhibited BTX and MWT with similar sweat reduction, but distinguishable odor and hair reduction at 1-year FU. These findings support individualized treatment approaches for axillary hyperhidrosis based on patient-specific symptoms and preferences.
Sections du résumé
Background
UNASSIGNED
Botulinum toxin A (BTX) and microwave thermolysis (MWT) represent 2 treatment modalities for axillary hyperhidrosis with different procedural and efficacy profiles.
Objective
UNASSIGNED
To compare long-term outcomes following BTX vs MWT treatment of axillary hyperhidrosis.
Methods
UNASSIGNED
A prospective, randomized, within-patient, controlled trial, treating axillary hyperhidrosis with contralateral BTX and MWT. Objective sweat measurement and patient-reported outcome measures for sweat and odor were collected at baseline, 6-month and 1-year follow-up (6M/1YFU). Hair reduction and patient treatment preference was also assessed.
Results
UNASSIGNED
Sweat reduction was significant (all
Limitations
UNASSIGNED
The intrinsic challenges in efficacy assessment.
Conclusion
UNASSIGNED
This study exhibited BTX and MWT with similar sweat reduction, but distinguishable odor and hair reduction at 1-year FU. These findings support individualized treatment approaches for axillary hyperhidrosis based on patient-specific symptoms and preferences.
Identifiants
pubmed: 38495540
doi: 10.1016/j.jdin.2023.12.011
pii: S2666-3287(24)00009-9
pmc: PMC10940128
doi:
Types de publication
Journal Article
Langues
eng
Pagination
91-99Informations de copyright
© 2024 by the American Academy of Dermatology, Inc. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Dr Haedersdal has received speaker honorarium for microwave thermolysis symposium. Drs Grove, Togsverd-Bo, and Zachariae have no conflicts of interest to declare.