Prospective evaluation of the RT-PCR based urinary marker Bladder Epicheck® as a diagnostic tool in upper urinary tract tumor.


Journal

Minerva urology and nephrology
ISSN: 2724-6442
Titre abrégé: Minerva Urol Nephrol
Pays: Italy
ID NLM: 101777299

Informations de publication

Date de publication:
18 Mar 2024
Historique:
medline: 19 3 2024
pubmed: 19 3 2024
entrez: 18 3 2024
Statut: aheadofprint

Résumé

Upper-tract-urothelial-carcinoma (UTUC) represents 5-10% of all urothelial-neoplasms with increasing incidence in the last decades. Current standard tools for diagnosis of UTUC include cytology, computed tomography (CT) urography and ureterorenoscopy (URS). The aim of this study was to evaluate the impact of Bladder Epicheck Overall, 136 urine samples, selective collected from upper-urinary-tract before URS for suspicion of UTUC were analyzed with cytology and Bladder Epicheck UTUC was detected in 40 cases (33.3%), among them 30 were classified as low-grade (LG) and 10 as high-grade (HG). Overall sensitivity of Bladder Epicheck Due to its high sensitivity for HG tumors, the Bladder Epicheck

Sections du résumé

BACKGROUND BACKGROUND
Upper-tract-urothelial-carcinoma (UTUC) represents 5-10% of all urothelial-neoplasms with increasing incidence in the last decades. Current standard tools for diagnosis of UTUC include cytology, computed tomography (CT) urography and ureterorenoscopy (URS). The aim of this study was to evaluate the impact of Bladder Epicheck
METHODS METHODS
Overall, 136 urine samples, selective collected from upper-urinary-tract before URS for suspicion of UTUC were analyzed with cytology and Bladder Epicheck
RESULTS RESULTS
UTUC was detected in 40 cases (33.3%), among them 30 were classified as low-grade (LG) and 10 as high-grade (HG). Overall sensitivity of Bladder Epicheck
CONCLUSIONS CONCLUSIONS
Due to its high sensitivity for HG tumors, the Bladder Epicheck

Identifiants

pubmed: 38498297
pii: S2724-6051.23.05488-5
doi: 10.23736/S2724-6051.23.05488-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Margherita Palermo (M)

Faculty of Medicine, Riga Latvia University, Riga, Latvia.

Carolina D'Elia (C)

Department of Urology, Central Hospital of Bolzano, Bolzano, Italy.

Emanuela Trenti (E)

Department of Urology, Central Hospital of Bolzano, Bolzano, Italy - trentiemanuela@yahoo.it.

Evi Comploj (E)

Department of Urology, Central Hospital of Bolzano, Bolzano, Italy.

Christine Mian (C)

Department of Pathology, Central Hospital of Bolzano, Bolzano, Italy.

Christine Schwienbacher (C)

Department of Pathology, Central Hospital of Bolzano, Bolzano, Italy.

Isabel Heidegger (I)

Department of Urology, Medical University of Innsbruck, Innsbruck, Austria.

Silvia Clauser (S)

Department of Urology, Central Hospital of Bolzano, Bolzano, Italy.

Armin Pycha (A)

Department of Urology, Central Hospital of Bolzano, Bolzano, Italy.
Medical School, Sigmund Freud Private University, Vienna, Austria.

Egils Vjaters (E)

Department of Urology, Riga Stradins University Hospital, Riga, Latvia.

Classifications MeSH