Chemical Composition of Artemisia Scoparia and Their Bioactivities.

Artemisia scoparia * Asteraceae * sesquiterpenes * single-crystal X-ray analysis * anti-inflammatory activity

Journal

Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449

Informations de publication

Date de publication:
18 Mar 2024
Historique:
revised: 15 03 2024
received: 17 02 2024
accepted: 18 03 2024
medline: 19 3 2024
pubmed: 19 3 2024
entrez: 19 3 2024
Statut: aheadofprint

Résumé

Three undescribed sesquiterpenes (1-3), two enantiomeric pairs of monoterpenes (4a/4b-5a/5b), one alkyne (6), two known alkynes (7-8) and eight known coumarins (9-16) were isolated from the aerial parts extracts of Artemisia scoparia. The structures of these compounds were fully elucidated by their 1D and 2D NMR, HRESIMS spectral data analyses, and comparison with literature. The absolute configurations of compounds were determined by single-crystal X-ray crystallography (1), a comparison of experimental and calculated electronic circular dichroism (ECD) data (2-6). 15 showed moderate inhibitory activity with the NO release in LPS-induced RAW264.7 cells. 9-16 showed varying degrees of promoting melanogenesis and tyrosinase activity in B16 cells.

Identifiants

DOI: 10.1002/cbdv.202400414 PMID: 38500337
pubmed: 38500337
doi: 10.1002/cbdv.202400414
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202400414

Informations de copyright

© 2024 Wiley-VCH GmbH.

Auteurs

Guziliayi Kuerban (G)

University of the Chinese Academy of Sciences, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing south road 40-1, Urumqi, CHINA.

Ablajan Turak (A)

Xinjiang Technical Institute of Physics and Chemistry, Key Laboratory of Plant Resources and Chemistry of Arid Zone, Urumqi 830011, PR China, Urumqi, CHINA.

Nurmirza Boymirzayevich Begmatov (NB)

S Yu Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, S.Yu.Yunusov Institute of the Chemistry of Plant Substances, Tashkent, Uzbekistan, Tashkent, UZBEKISTAN.

Jiangyu Zhao (J)

Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, PR China, Urumqi, CHINA.

Haji Akber Aisa (HA)

Xinjiang Technical Institute of Physics and Chemistry, key laboratory of chemistry of plant resources in arid reagions, beijing south road 40-1, 830011, urumqi, CHINA.

Classifications MeSH