Respiratory function after 30+ years following sulfur mustard exposure in survivors in Sweden.
Halabja
impulse oscillometry
multiple breath washout
pulmonary disease
small airways
sulfur mustard
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2024
2024
Historique:
received:
01
07
2023
accepted:
14
02
2024
medline:
19
3
2024
pubmed:
19
3
2024
entrez:
19
3
2024
Statut:
epublish
Résumé
Sulfur mustard (SM) exposure causes acute and chronic respiratory diseases. The extent of small airway dysfunction (SAD) in individuals exposed to SM is unclear. This study evaluated and compared SAD in SM-exposed and SM-unexposed participants using noninvasive lung function tests assessing small airway function. This retrospective cohort study involved SM-exposed ( No statistically significant differences in age, height, or body mass index were observed between the two groups. IOS showed significantly increased small airway resistance, while N Exposure to SM was positively associated with long-term impairment of respiratory tract function in the small airways in the majority of the previously SM-exposed individuals in the present study. Furthermore, both IOS and N
Sections du résumé
Background
UNASSIGNED
Sulfur mustard (SM) exposure causes acute and chronic respiratory diseases. The extent of small airway dysfunction (SAD) in individuals exposed to SM is unclear. This study evaluated and compared SAD in SM-exposed and SM-unexposed participants using noninvasive lung function tests assessing small airway function.
Methods
UNASSIGNED
This retrospective cohort study involved SM-exposed (
Results
UNASSIGNED
No statistically significant differences in age, height, or body mass index were observed between the two groups. IOS showed significantly increased small airway resistance, while N
Conclusion
UNASSIGNED
Exposure to SM was positively associated with long-term impairment of respiratory tract function in the small airways in the majority of the previously SM-exposed individuals in the present study. Furthermore, both IOS and N
Identifiants
pubmed: 38500955
doi: 10.3389/fmed.2024.1251500
pmc: PMC10945011
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1251500Informations de copyright
Copyright © 2024 Moradi, Kjellberg, Li, Daka and Olin.
Déclaration de conflit d'intérêts
A-CO has invented a method to examine small airways, the PExA method, and is a shareholder and board member of PExA AB. However, results from that method are not presented in the current manuscript. She is also a scientific adviser for a pharmacological study carried out by Chiesi AB. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.