Iron status in piglets at three days of age and at weaning and possible seasonal effects on the blood haemoglobin levels in a Swedish outdoor pig-producing farm.

Iron deficiency anaemia Suckling piglet Swine

Journal

Acta veterinaria Scandinavica

ISSN: 1751-0147

Titre abrégé: Acta Vet Scand

Pays: England

ID NLM: 0370400

Informations de publication

Date de publication:
19 Mar 2024

Historique:

received: 19 12 2023

accepted: 11 03 2024

medline: 20 3 2024

pubmed: 20 3 2024

entrez: 20 3 2024

Statut: epublish

Résumé

Piglets are born with limited stores of iron, and with an increasing number of live-born piglets, there may be a risk that the sows cannot provide enough iron to their offspring. The iron content in soil may not meet the demands of today's piglet, born and reared in an outdoor setting. The study aimed to describe the blood haemoglobin (Hb) levels in pigs reared outdoors and to determine whether piglets have higher Hb levels at weaning when an iron supplement is administered intramuscularly at three days of age, as compared to pigs not given an iron supplement. The seasonal variation in Hb-levels was also to be investigated. The Hb concentration was analysed with a HemoCue 201 + Hb photometer. In total 56 litters (399 piglets) were included in the study and sampled at three days of age, while 378 piglets were sampled at weaning. The mean Hb level at three days of age was 91 g/L (48-154 g/L). In total 47% of the piglets had Hb levels < 90 g/L at three days of age. The mean Hb level at weaning was 127 g/L (76-176 g/L), with a lower level (122 g/L) in the group given the iron supplement than in the group not given an iron supplement (132 g/L). Only 1% of the piglets had Hb levels lower than 90 g/L at weaning. Results indicative of a seasonal effect on Hb levels at three days of age was demonstrated. Piglets born in spring had significantly lower Hb levels, and piglets born in autumn had significantly higher Hb levels. No seasonal effect could be demonstrated for Hb levels at day 33. The results indicate that the natural uptake from the environment was sufficient, but that there was a seasonal effect on the Hb levels at three days of age. This indicates that there might be a need for different routines regarding iron supplementation in outdoor reared piglets depending on the climate and season.

Sections du résumé

BACKGROUND BACKGROUND

RESULTS RESULTS

In total 56 litters (399 piglets) were included in the study and sampled at three days of age, while 378 piglets were sampled at weaning. The mean Hb level at three days of age was 91 g/L (48-154 g/L). In total 47% of the piglets had Hb levels < 90 g/L at three days of age. The mean Hb level at weaning was 127 g/L (76-176 g/L), with a lower level (122 g/L) in the group given the iron supplement than in the group not given an iron supplement (132 g/L). Only 1% of the piglets had Hb levels lower than 90 g/L at weaning. Results indicative of a seasonal effect on Hb levels at three days of age was demonstrated. Piglets born in spring had significantly lower Hb levels, and piglets born in autumn had significantly higher Hb levels. No seasonal effect could be demonstrated for Hb levels at day 33.

CONCLUSIONS CONCLUSIONS

The results indicate that the natural uptake from the environment was sufficient, but that there was a seasonal effect on the Hb levels at three days of age. This indicates that there might be a need for different routines regarding iron supplementation in outdoor reared piglets depending on the climate and season.

Identifiants

DOI: 10.1186/s13028-024-00735-z PMID: 38504355

pubmed: 38504355

doi: 10.1186/s13028-024-00735-z

pii: 10.1186/s13028-024-00735-z

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

Informations de copyright

Références

Svoboda M, Drabek J. Iron deficiency in suckling piglets; ethiology, clinical aspects and diagnosis. Folia Vet. 2005;49:104–11.

Egeli AK, Framstad T. Evaluation of the efficacy of perorally administered glutamic acid-chelated iron and iron-dextran injected subcutaneously in Duroc and Norwegian landrace piglets. Zentralbl Veterinarmed A. 1998;45:53–61.

doi: 10.1111/j.1439-0442.1998.tb00800.x pubmed: 9557127

Szudzik M, Starzynski RR, Jonczy A, Mazgaj R, Lenartowicz M, Lipinski P. Iron supplementation in suckling piglets: an ostensibly easy therapy of neonatal iron deficiency anemia. Pharmaceuticals. 2018;11:128.

doi: 10.3390/ph11040128 pubmed: 30467279 pmcid: 6315738

Shields RG, Mahan DC, Graham PL. Changes in swine body composition from birth to 145 kg. J Anim Sci. 1983;57:43–54.

doi: 10.2527/jas1983.57143x pubmed: 6885664

Hurley WL. Composition of sow colostrum and milk. In: Farmer C, editor. The gestating and lactating sow. Wageningen: Wageningen Academic; 2015. pp. 193–229.

Robinson NA, Loynachan AT. Cardiovascular and hematopoietic systems. In: Zimmerman, JJ, Karriker LA, Romirez A, Schwartz KJ, Stevenson GW, Zhang J, editors. Diseases of Swine, 11th Edition. Ames, Iowa: Wiley-Blackwell; 2019;223–33.

Bhattarai S, Nielsen JP. Early indicators of iron deficiency in large piglets at weaning. J Swine Health Prod. 2015;23:10–7.

Perri AM, Friendship RM, Harding JCS, O’Sullivan TL. An investigation of iron deficiency and anemia in piglets and the effect of iron status at weaning on post-weaning performance. J Swine Health Prod. 2016;24:10–20.

Brown JME, Edwards SA, Smith WJ, Thompson E, Duncan J. Welfare and production implications of teeth clipping and iron injection of piglets in outdoor systems in Scotland. Prev Vet Med. 1996;27:95–105.

doi: 10.1016/0167-5877(96)01013-6

Kleinbeck AN, McGlone JJ. Intensive indoor versus outdoor swine production systems: genotype and supplemental iron effects on blood haemoglobin and selected immune measures in young pigs. J Anim Sci. 1999;77:2384–90.

doi: 10.2527/1999.7792384x pubmed: 10492444

Stern S, Sjölund M, Fellström C, Sterning M, Andersson K. Red blood cell parameters in piglets reared outdoors or indoors. Proceedings of the 16th IPVS Congress, Melbourne, Australia. 2000;192.

Prunier A, Leblanc-Maridor M, Pauwels M, Jaillardon L, Belloc C, Merlot E. Evaluation of the potential benefits of iron supplementation in organic pig farming. Open Res Europe. 2022;2:11.

doi: 10.12688/openreseurope.14367.2

Colombo C, Palumbo G, He JZ, Pinton R, Cesco S. Review on iron availability in soil: interaction of Fe minerals, plants, and microbes. J Soils Sediments. 2014;14:538–48.

doi: 10.1007/s11368-013-0814-z

Szabo P, Bilkei G. Iron deficiency in outdoor pig production. J Vet Med Physiol Pathol Clin Med. 2002;49:390–91.

doi: 10.1046/j.1439-0442.2002.00448.x

Pearson RB. A UK farm study to evaluate productive parameters following routine iron injection of outdoor piglets. Proceedings of the 21st IPVS Congress, Vancouver, Canada. 2012;1036.

Farm. & Animal Health national pig production records database. Farm & Animal Health, Sweden. 2021. https://www.gardochdjurhalsan.se/winpig/medeltal-och-topplistor/medeltal-suggor/ . Accessed 20 Oct 2021.

The Swedish meteorological and hydrological database. The Swedish meteorological and hydrological institute. 2023. https://www.smhi.se/data/ladda-ner-data/griddade-nederbord-och-temperaturdata-pthbv . Accessed 6 Jul 2023.

Kutter APN, Mauch JY, Riond B, Martin-Jurado O, Spielmann N, Weiss M, et al. Evaluation of two devices for point-of-care testing of haemoglobin in neonatal pigs. Lab Anim. 2012;46:65–70.

doi: 10.1258/la.2011.011086 pubmed: 22087030

Sergeant ESG. Epitools epidemiological calculators. Ausvet. 2018. Available from: http://epitools.ausvet.com.au

Microsoft Corporation. Microsoft Excel 2018. Available from: https://office.microsoft.com/excel

SAS® version 9.4 (SAS Institute Inc. Cary, USA).

Lipiński P, Starzyński RR, Canonne-Hergaux F, Tudek B, Oliński R, Kowalczyk P, et al. Benefits and risks of iron supplementation in anemic neonatal pigs. Am J Pathol. 2010;177:1233–43.

doi: 10.2353/ajpath.2010.091020 pubmed: 20805566 pmcid: 2928957

Heidbüchel K, Raabe J, Baldinger L, Hagmüller W, Bussemas R. One iron injection is not enough - iron status and growth of suckling piglets on an organic farm. Animals. 2019;9:651.

doi: 10.3390/ani9090651 pubmed: 31487865 pmcid: 6770926

Pu Y, Guo B, Liu D, Xiong H, Wang Y, Du H. Iron supplementation attenuates the inflammatory status of anemic piglets by regulating hepcidin. Biol Trace Elem Res. 2015;167:28–35.

doi: 10.1007/s12011-015-0295-6 pubmed: 25774043

Joachim A, Shrestha A, Freudenschuss B, Palmieri N, Hinney B, Karembe H, et al. Comparison of an injectable toltrazuril-gleptoferron (Forceris®) and an oral toltrazuril (Baycox®) + injectable iron dextran for the control of experimentally induced piglet cystoisosporosis. Parasites Vectors. 2018;11:206.

doi: 10.1186/s13071-018-2797-5 pubmed: 29580269 pmcid: 5870915

Buffler M, Becker C, Windisch WM. Effects of different iron supply to pregnant sows (Sus scrofa Domestica L.) on reproductive performance as well as iron status of new-born piglets. Arch Anim Nutr. 2017;71:219–30.

doi: 10.1080/1745039X.2017.1301059 pubmed: 28293962

Beskow P, Norqvist M, Lundeheim N, Wallgren P. Utomhusproduktion Av Grisar i Norrland. Svensk Veterinärtidning. 2003;4:11–21.