DNM3OS/miR-127-5p/CDH11, activates Wnt3a/β-catenin/LEF-1 pathway to form a positive feedback and aggravate spine facet joint osteoarthritis.

DNM3OS Spinal facet joint osteoarthritis Wnt/β-Catenin/LEF-1 ceRNA network miR-127-5p

Journal

Non-coding RNA research
ISSN: 2468-0540
Titre abrégé: Noncoding RNA Res
Pays: Netherlands
ID NLM: 101688191

Informations de publication

Date de publication:
Jun 2024
Historique:
received: 12 11 2023
revised: 03 01 2024
accepted: 11 01 2024
medline: 20 3 2024
pubmed: 20 3 2024
entrez: 20 3 2024
Statut: epublish

Résumé

Spinal facet joint osteoarthritis (FJOA) is an OA disease with pathogenesis and progression uncovered. Our present study was performed to elucidate the role of DNM3OS on spinal FJOA. In this study, spine facet joint tissue of patients were collected.

Identifiants

pubmed: 38505310
doi: 10.1016/j.ncrna.2024.01.008
pii: S2468-0540(24)00008-8
pmc: PMC10945139
doi:

Types de publication

Journal Article

Langues

eng

Pagination

294-306

Informations de copyright

© 2024 The Authors.

Auteurs

Jing Wang (J)

Department of Orthopaedics, Zhongshan Torch Development Zone People's Hospital, Zhongshan, 528436, China.

Zhenyu Yang (Z)

Southern Medical University, Guangzhou, 510220, China.

Xiuming He (X)

Department of Orthopaedics, Zhongshan Torch Development Zone People's Hospital, Zhongshan, 528436, China.

Yeyang Wang (Y)

The Spine Department, Orthopaedic Center, Guangdong Second Provincial General Hospital, Guangzhou, 510220, China.

Dixin Luo (D)

The Spine Department, Orthopaedic Center, Guangdong Second Provincial General Hospital, Guangzhou, 510220, China.

Wangyang Xu (W)

The Spine Department, Orthopaedic Center, Guangdong Second Provincial General Hospital, Guangzhou, 510220, China.

Hongtao Zhang (H)

Department of Orthopaedics, Zhongshan Torch Development Zone People's Hospital, Zhongshan, 528436, China.

Xiaozhong Zhou (X)

Southern Medical University, Guangzhou, 510220, China.
The Spine Department, Orthopaedic Center, Guangdong Second Provincial General Hospital, Guangzhou, 510220, China.
Department of Orthopedics, Hui Lai County People's Hospital of Guangdong Second Provincial General Hospital, Hui Lai, 515299, China.

Classifications MeSH