The Option of Chronotherapy of Hypertension.
Journal
Cardiology in review
ISSN: 1538-4683
Titre abrégé: Cardiol Rev
Pays: United States
ID NLM: 9304686
Informations de publication
Date de publication:
20 Mar 2024
20 Mar 2024
Historique:
medline:
20
3
2024
pubmed:
20
3
2024
entrez:
20
3
2024
Statut:
aheadofprint
Résumé
The aim of the present paper is to explore the option of chronotherapy of hypertension and its effectiveness in blood pressure (BP) lowering compared with its standard daily treatment. The treatment of BP has gone through many different schemes over the years. From no treatment in the early 1930s, to step care, to multiple drug combinations, or to single daily drug combinations with 2-3 drugs, still BP is not well controlled in a significant number of patients. Recently, the role of the circadian rhythm in the treatment of hypertension has been tested by several studies comparing the evening versus the morning drug administration with no clear evidence of superiority of either mode of drug administration. However, in cases of morning surge of BP, nocturnal hypertension, and renal disease, the evening drug administration has been more effective than the morning drug administration, and thus, more preferable. In order to get a better perspective on this approach of hypertension treatment, a Medline search of the English literature was contacted between 2010 and 2023 using the terms BP control, circadian rhythm, morning drug administration, evening drug administration, and 38 pertinent papers were selected for analysis. Careful review of the selected papers showed that chronotherapy of hypertension is effective. However, the overall effectiveness of evening drug administration compared with the morning administration is not significantly more effective compared to the morning administration and more work is needed in this field.
Identifiants
pubmed: 38506526
doi: 10.1097/CRD.0000000000000644
pii: 00045415-990000000-00234
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure: The authors have no conflicts of interest to report.
Références
Hay JH. The significance of a raised blood pressure. BMJ. 1931;2:274–274.
White PD. Heart Disease. 2nd ed. MacMillan co; 1937:326
Veterans Administration Cooperative Study Group. Effects of treatment on morbidity in hypertension results in patients with diastolic blood pressure averaging 115 through 123 mmHg. JAMA. 1067;202:1028–1034.
Veterans Administration Cooperative Study Group on Antihypertensive Agents. Effects of treatment on morbidity in hypertension results in patients with diastolic blood pressure 90 through 114 mmHg. JAMA. 1970;213:1143–1152.
Report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure: a cooperative study. JAMA. 1977;237:255–261.
The 1980 report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure. Arch Intern Med. 1980;140:1280–1285.
Joint National Committee on detection, evaluation, and treatment of high blood pressure. The 1984 report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure. Arch Intern Med. 1984;144:1045–1057.
Joint National Committee on detection, evaluation, and treatment of high blood pressure. The 1988 report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure. Arch Intern Med. 1988;148:1023–1038.
Joint National committee on detection, evaluation, and treatment of high blood pressure. The 5th report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure (JNC V). Arch Intern Med. 1993;153:154–183.
Joint National Committee on detection, evaluation, and treatment of high blood pressure. The 6th report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure. Arch Intern Med. 1997;157:2433–2446.
Joint National Committee on detection, evaluation, and treatment of high blood pressure. The 7th report of the Joint National Committee on detection, evaluation, and treatment of high blood pressure. JAMA. 2003;289:2560–2572.
Williams B, Lindholm LH, Sever B. Systolic blood pressure is all that matters. Lancet. 2008;371:2219–2221.
Cushman WC, Evans GW, Byington RP, et al.; ACCORD Study Group. Effects of intensive blood pressure control in type 2 diabetes mellitus the ACCORD Study Group. N Engl J Med. 2010;362:1575–1585.
Wright JT Jr, Williamson JD, Whelton PK, et al.; SPRINT Research Group. A randomized trial of intensive versus standard blood pressure control (SPRINT). N Engl J Med. 2015;373:2103–2116.
Wheton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA et al, guidelines for the prevention, detection, evaluation, and management of high blood pressure in adults a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018;71:e13–e115.
Williams B, Mancia G, Spiering W, et al.; Authors/Task Force Members:. 2018 ESC/ESH guidelines for the management of arterial hypertension the task force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. J Hypertens. 2018;36:1953–2041.
Calhoun DA, Schiffrin EL, Flack JM. Resistant hypertension: an update. Am J Hypertens. 2019;32:1–3.
Petersen J, Malyutina S, Ryabikov A, et al. Uncontrolled and apparent treatment resistant hypertension: a cross-sectional study of Russian and Norwegian 40-69 year olds. BMC Cardiovasc Disord. 2020;20:135.
Kario K, Hoshide S, Mogi M. Uncontrolled hypertension: the greatest challenge and perspectives in Asia. Hypertens Res. 2022;45:1847–1849.
Gumz ML, Shimbo D, Abdalla M, et al. Toward precision medicine: circadian rhythm of blood pressure and chronotherapy for hypertension-2021 NHLBI workshop report. Hypertension. 2023;80:503–522.
Giffett K, Burris TP. The mammalian clock and chronopharmacology. Bioorg Med Chem Lett. 2013;23:1929–1934.
Klerman EB, Brager A, Carskadon MA, et al. Keeping an eye on circadian time in clinical research and medicine. Clin Transl Med. 2022;12:e1131.
Cederroth CR, Albrecht U, Bass J, et al. Medicine in the fourth dimension. Cell Metab. 2019;30:238–250.
Douma LG, Gumz ML. Circadian clock-mediated regulation of blood pressure. Free Radic Biol Med. 2018;119:108–114.
Kario K. Morning surge in blood pressure and cardiovascular risk. Hypertension. 2010;56:765–773.
Hermida RC, Ayala DE, Mojon A, et al. Influence of the circadian time of hypertension treatment on cardiovascular risk: results of the MAPEC study. Chronobiol Int. 2010;27:1629–1651.
Bowls NP, Thosar SS, Herzig MX, et al. Chronotherapy of hypertension. Curr Hypertens Rep. 2019;20:97.
Schillaci G, Battista F, Settini L, et al. Antihypertensive drug treatment and circadian blood pressure rhythm: a review of the role of chronotherapy in hypertension. Curr Pharm Des. 2015;21:756–772.
White WB. A chronotherapeutic approach to the management of hypertension. Am J Hypertens. 1996;9:29S–33S.
Sajan J, Chiu TA, Chacko AJ, et al. Chronotherapeutics and chronotherapeutic drug delivery systems. Trop J Pharm Res. 2009;8:467–475.
Okeahialam BN, Ohihoin EN, Ayutucjukwu JNA. Diuretic drugs benefit patients with hypertension more with night-time dosing. Ther Adv Drug Safety. 2012;3:273–278.
Stranges PM, Drew AM, Rafferty P, et al. Treatment of hypertension with chronotherapy: is it time of drug administration? Ann Pharmacother. 2015;49:323–334.
Cortes-Rios J, Hermida RC, Rodriguez-Fernandez M. Dosing time optimization of antihypertensive medications by including the circadian rhythm in pharmacokinetic-pharmacodynamic models. PLoS Comput Biol. 2022;18:e1010711.
Chrysant SG. Relatability of blood pressure monitoring with wearable cuffless devices. Am J Cardiol. 2022;169:145–147.
Kasiakoglas A, Tsioufis C, Thomopoulos C, et al. Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea: a cross-over study. J Hypertens. 2015;33:393–400.
Jiang H, Yu Z, Liu J, et al. Bedtime administration of antihypertensive medication can reduce morning blood pressure surges in hypertensive patients: a systematic review and meta-analysis. Ann Palliat Med. 2021;10:6841–6849.
Sun Y, Yu X, Liu J, et al. Effect of bedtime administration of blood pressure lowering agents on ambulatory blood pressure monitoring results: a meta-analysis. Cardiol J. 2016;23:473–481.
Hjorkjaer HO, Jensen T, Kofoed KF, et al. Nocturnal antihypertensive treatment in patients with type 1 diabetes with autonomic neuropathy and non-dipping: a randomized, placebo-controlled, double-blind cross-over trial. BMJ Open. 2016;6:e012307.
Wang C, Ye Y, Liu C, et al. Evening versus morning dosing regimen during therapy for chronic kidney disease patients with hypertension in blood pressure patterns: a systematic review and meta-analysis. Int Med J. 2017;47:900–906.
Luo Y, Ren L, Jiang M, et al. Antihypertensive efficacy of amlodipine dosing during morning versus evening: a meta-analysis. Rev Cardiovasc Med. 2019;20:91–98.
Hermida RC, Ayala DE, Mojon A, et al. Influence of circadian time of hypertension treatment on cardiovascular risk: results of the MAPEC study. Chronobiol Int. 2010;27:1629–1651.
Hermida RC, Crespo JJ, Dominguez-Sardina M, et al.; Hygia Project Investigators. Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia chronotherapy trial. Eur Heart J. 2020;41:4565–4576.
MacKenzie IS, Rogers A, Poulter NR, et al.; TIME Study Group. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomized, open-label, blind-end-point trial. Lancet. 2022;400:1417–1425.
Zhao J, Zeng Y, Weng J, et al. Evening versus morning administration of drug therapy for hypertension: a meta-analysis of randomized controlled trials. Eur J Integr Med. 2022;50:102111.
Lafeber M, Grobbee DE, Schrover LM, et al. Comparison of a morning polypill, evening polypill and individual pills on LDL-cholesterol, ambulatory blood pressure and adherence in high-risk patients: a randomized crossover trial. Int J Cardiol. 2015;181:193–199.
Zappe DH, Crikelair N, Kandra A, et al. Time of administration important? Morning versus evening dosing of valsartan. J Hypertens. 2015;33:385–392.
Serinel Y, Yee BJ, Grunstein RR, et al. Chronotherapy for hypertension in obstructive sleep apnoea (CHOSA): a randomized, double-blind, placebo-controlled crossover trial. Thorax. 2017;72:550–558.
Fujiwara T, Hoshide S, Yano Y, et al. Comparison of morning vs bedtime administration of valsartan/amlodipine on nocturnal brachial and central blood pressure in patients with hypertension. J Clin Hypertens. 2017;19:1319–1326.
Poulter NR, Savopoulos C, Anjum A, et al. Randomized crossover trial of the impact of morning or evening dosing of antihypertensive agents on 24-hour ambulatory blood pressure The HARMONY trial. Hypertension. 2018;72:870–873.
Kuate LM, Bongha Ondoa HO, Katte JC, et al. Effects of morning versus evening administration of perindopril on the circadian control of blood pressure in cameroonian type 2 diabetes individuals: a crossover randomized trial. Atch Cardiovasc Dis. 2019;3:3014.
Lecapentier Y, Sxhussler O, Hebert JL, et al. Molecular mechanisms underlying the circadian rhythm of blood pressure in normotensive subjects. Curr Hypertens Rep. 2020;22:50.
Zhang J, Sun R, Jiang T, et al. Circadian blood pressure rhythm in cardiovascular and renal health and disease. Biomolecules. 2021;11:8868.
Booth JN III, Jaeger BC, Huanng L, et al. Morning blood pressure surge and cardiovascular disease events and all-cause mortality in blacks: the Jackson Heart Study. Hypertension. 2020;75:835–843.
Narita K, Hoshide S, Kario K. Differences between morning and evening home blood pressure and cardiovascular events: the J-HOP study (Japan Morning Surge-Home Blood Pressure). Hypertens Res. 2021;44:1597–1605.
Gong S, Liu K, Ye R, et al. Nocturnal dipping status and the association of morning blood pressure surge with subclinical target organ damage in untreated hypertensives. J Clin Hypertens (Greenwich). 2019;21:1286–1294.
Sigunuru GP, Kario K, Shin J, et al. HOPE Asia Network Morning surge in blood pressure and blood pressure variability in Asia: evidence statement from the HOPE Asia Network. J Clin Hypertens. 2019;21:324–334.
Parati G, Torlasco C, Pengo M, et al. Blood pressure variability: its relevance for cardiovascular homeostasis and cardiovascular diseases. Hypertens Res. 2020;43:609–620.
Kario K, Hoshide S, Mizuno H, et al.; JAMP Study Group. Nighttime blood pressure phenotype and cardiovascular prognosis. Circulation. 2020;142:1810–1820.
Akhtar N, Al-Jerdi S, Kamran S, et al. Night-time non-dipping blood pressure and heart rate: an association with the risk of silent small vessel disease in patients presenting with acute ischemic stroke. Front Neurol. 2021;12:719311.
Lo L, Hung SWS, Chan SSW, et al. Prognostic value of nocturnal blood pressure dipping on cardiovascular outcomes in Chinese patients with hypertension in primary care. J Clin Hypertens (Greenwich). 2021;23:1291–1299.
Huart J, Persu A, Langele JP, et al. Pathophysiology of nondipping blood pressure pattern. Hypertension. 2023;80:719–729.
Awad K, Serban MC, Penson P, et al.; Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group. Effects of morning vs evening statin administration on lipid profile: a systematic review and meta-analysis. J Clin Lipidol. 2017;11:972–985.e9.
Yi YJ, Kim HJ, Jo SK, et al. Comparison of the efficacy and safety of morning administration of controlled-release simvastatin versus evening administration of immediate-release simvastatin in chronic kidney disease patients with dyslipidemia. Clin Ther. 2014;36:1182–1190.
Schachter M. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundam Clin Pharmacol. 2005;19:117–125.
Krasifiska B, Paluszkiewicz L, Miciak-Lawicka E, et al. The effect of acetylsalycilic acid dosed at bedtime on the anti-aggregation effect in patients with coronary heart disease and arterial hypertension: a randomized, controlled trial. Cardiol J. 2019;26:727–735.
Van Diemen JJK, Fuijkeschot WW, Wessels TJ, et al. Evening intake of aspirin is associated with more stable 24-h platelet inhibition compared to morning intake: a study of chronic aspirin users. Platelets. 2016;27:351–356.
Martino TA, Harrington ME. The time for circadian medicine. J Biol Rhythms. 2020;35:419–420.
Kramer A, Lange T, Sples C, et al. Foundations of circadian medicine. PLoS Biol. 2022;20:e3001567.
Cederroth CR, Albrecht U, Bass J, et al. Medicine in the fourth dimention. Cell Metab. 2019;30:238–250.
Lemmer B, Middeke M. A commentary on the Spanish hypertension studies MAPEC and HYGIA. Chronobiol Int. 2020;37:1269.
Brunstrom M, Kjeldsen SE, Kreutz R, et al. Missing verification of source data in hypertension research: the HYGIA PROJECT in perspective. Hypertension. 2021;78:555–558.
Turgeon RD, Althouse AD, Cohen JB, et al. Lowering nighttime blood pressure with bedtime dosing of antihypertensive medications controversies in hypertension- con side of the argument. Hypertension. 2021;78:871–878.
Hermida RC, Mojon A, Smolensky MH, et al. Lowering nighttime blood pressure with bedtime dosing of antihypertensive medications controversies in hypertension-pro side of the argument. Hypertension. 2021;78:879–893.
Setrgiou G, Brunstrom M, MacDonald T, et al. Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension. J Hypertens. 2022;40:1847–1858.
Burnier M, Kreutz R, Narkiewicz K, et al. Circadian variations in blood pressure and their implications for the administration of antihypertensive drugs: is dosing in the evening better than the morning? J Hypertens. 2020;38:1396–1406.
Liu X, Huang W, Leo S, et al. Evening versus morning dosing drug therapy for chronic kidney disease patients with hypertension: a systematic review. Kidney Blood Press Res. 2014;39:427–440.
MacKenzie I, Rogers A, Poulter NR, et al. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomized, open-label, blinded-endpoint clinical trial. Lancet. 2022;400:1417–1425.
Garrison SR, Kober MR, Allan GM, et al. Bedtime versus morning use of antihypertensives for cardiovascular risk reduction (BedMed): protocol for a prospective, randomised, open-label, blinded end point pragmatic trial. BMJ Open. 2022;12:e059711.
Garrison SR, Youngson E, Perry DA, et al. Bedtime versus morning use of antihypertensives in frail continuing care residents (BedMed-Frail): protocol for a prospective, randomized, open-label, blinded endpoint pragmatic trial. BMJ Open. 2023;13:e074777.