VIDEOFLUOROSCOPIC EVALUATION OF THE IMPACT OF CAPSULE SIZE AND SUBJECT'S AGE AND GENDER ON CAPSULE SWALLOWING.
Journal
Arquivos de gastroenterologia
ISSN: 1678-4219
Titre abrégé: Arq Gastroenterol
Pays: Brazil
ID NLM: 15310600R
Informations de publication
Date de publication:
2024
2024
Historique:
received:
19
06
2023
accepted:
14
01
2024
medline:
21
3
2024
pubmed:
21
3
2024
entrez:
21
3
2024
Statut:
epublish
Résumé
People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals. To evaluate the impact of capsule size and adults' age and gender on oral and pharyngeal capsule transit during capsule swallows. Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years). Smaller capsules were filled with 0.50 mL of barium sulfate, and larger capsules were filled with 0.95 mL of barium sulfate; the volume of liquid ingested with the capsules was also quantified in each ingestion. The measurements included the oral preparation time, oral transit time, swallowing reaction time, time to laryngeal vestibule closure, laryngeal vestibule closure duration, pharyngeal transit time, and upper esophageal sphincter opening duration. The capsule size did not influence either the oral or pharyngeal transit time. Increased liquid volume was ingested with larger capsules and by people older than 40 years. The oral transit time was shorter in older adults (60-88 years), and the time to laryngeal vestibule closure was longer in women. The size of large capsules did not make a difference in oral or pharyngeal transit when compared with smaller capsules. The capsule size and the participant's age influenced the volume of liquid ingested - larger capsules and older individuals required a larger volume. The capsule oral transit was faster in individuals older than 60 years. •Swallowing is influenced by the characteristics of what is being swallowed. •There was no difference in swallowing capsules containing 0.50 mL or 0.95 mL. •Larger capsules need more liquid ingestion to make swallowing easier. •Individuals older than 40 years need a greater volume of liquid to swallow capsules than younger adults.
Sections du résumé
BACKGROUND
BACKGROUND
People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals.
OBJECTIVE
OBJECTIVE
To evaluate the impact of capsule size and adults' age and gender on oral and pharyngeal capsule transit during capsule swallows.
METHODS
METHODS
Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years). Smaller capsules were filled with 0.50 mL of barium sulfate, and larger capsules were filled with 0.95 mL of barium sulfate; the volume of liquid ingested with the capsules was also quantified in each ingestion. The measurements included the oral preparation time, oral transit time, swallowing reaction time, time to laryngeal vestibule closure, laryngeal vestibule closure duration, pharyngeal transit time, and upper esophageal sphincter opening duration.
RESULTS
RESULTS
The capsule size did not influence either the oral or pharyngeal transit time. Increased liquid volume was ingested with larger capsules and by people older than 40 years. The oral transit time was shorter in older adults (60-88 years), and the time to laryngeal vestibule closure was longer in women.
CONCLUSION
CONCLUSIONS
The size of large capsules did not make a difference in oral or pharyngeal transit when compared with smaller capsules. The capsule size and the participant's age influenced the volume of liquid ingested - larger capsules and older individuals required a larger volume. The capsule oral transit was faster in individuals older than 60 years.
BACKGROUND
BACKGROUND
•Swallowing is influenced by the characteristics of what is being swallowed.
BACKGROUND
BACKGROUND
•There was no difference in swallowing capsules containing 0.50 mL or 0.95 mL.
BACKGROUND
BACKGROUND
•Larger capsules need more liquid ingestion to make swallowing easier.
BACKGROUND
BACKGROUND
•Individuals older than 40 years need a greater volume of liquid to swallow capsules than younger adults.
Identifiants
pubmed: 38511792
pii: S0004-28032024000100300
doi: 10.1590/S0004-2803.246102023-92
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM