A Human Immunodeficiency Virus Superinfection Diagnosed in a Patient on Intramuscular Long-acting Combination of Cabotegravir and Rilpivirine.

HIV cabotegravir genotyping long-acting injectable therapy rilpivirine

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
21 Mar 2024
Historique:
received: 27 09 2023
medline: 21 3 2024
pubmed: 21 3 2024
entrez: 21 3 2024
Statut: aheadofprint

Résumé

A case of a male with human immunodeficiency virus with plasma genotyping detecting no resistance and a CRF02_AG subtype had a controlled HIV RNA on antiretroviral therapy since 2010. We introduced intramuscular therapy with cabotegravir and rilpivirine. One month later, his HIV RNA was 1500 copies/mL; genotyping found a subtype B with many mutations.

Identifiants

pubmed: 38513236
pii: 7633177
doi: 10.1093/cid/ciad757
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

Déclaration de conflit d'intérêts

Potential conflicts of interest. N. V. received payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from VIIV. S. L. N. received payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from MSD and GILEAD; payment for expert testimony from GILEAD; support for attending meetings and/or travel from GILEAD and VIIV; and participated on a Data Safety Monitoring Board or Advisory Board for GILEAD. E. T. received payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from VIIV. J. L. M. received payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from VIIV; support for attending meetings and/or travel from VIIV, MSD, and Gilead. L. M. J. received payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from ViiV, Merck, and GILEAD; support for attending meetings and/or travel from Gilead and MSD; and participated on a data safety monitoring board or advisory board for ViiV and Gilead. K. L. received grants or contracts from Gilead, MSD, and ViiV Healthcare; consulting fees from Gilead, ViiV Healthcare, and MSD; payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Gilead, ViiV Healthcare, and MSD; and support for attending meetings and/or travel from Gilead, ViiV Healthcare, and MSD. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

Auteurs

Nadia Valin (N)

Department of Infectious and Tropical Diseases, Saint Antoine Hospital, Paris, France.

Sidonie Lambert-Niclot (S)

Virology Department, Sorbonne University, Saint-Antoine Hospital, AP-HP, Pierre Louis Epidemiology and Public Health Institute (iPLESP), INSERM 1136, Paris, France.

Emma Torres (E)

Department of Infectious and Tropical Diseases, Saint Antoine Hospital, Paris, France.

Jean Luc Meynard (JL)

Department of Infectious and Tropical Diseases, Saint Antoine Hospital, Paris, France.

Claire Périllaud-Dubois (C)

Virology Department, Sorbonne University, Saint-Antoine Hospital, AP-HP, Pierre Louis Epidemiology and Public Health Institute (iPLESP), INSERM 1136, Paris, France.

Laurence Morand-Joubert (L)

Virology Department, Sorbonne University, Saint-Antoine Hospital, AP-HP, Pierre Louis Epidemiology and Public Health Institute (iPLESP), INSERM 1136, Paris, France.

Karine Lacombe (K)

Department of Infectious and Tropical Diseases, Saint Antoine Hospital, Paris, France.
Pierre Louis Institute of Public Health, Sorbonne Université, Inserm UMR-S1136, Paris, France.

Classifications MeSH