Early intravenous magnesium sulfate and its impact on cerebral vasospasm as well as delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: A retrospective matched case-control analysis.

aneurysmal subarachnoid hemorrhage cerebral vasospasm delayed cerebral ischemia functional outcome magnesium sulfate

Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
19 Mar 2024
Historique:
received: 16 02 2024
accepted: 13 03 2024
medline: 22 3 2024
pubmed: 22 3 2024
entrez: 21 3 2024
Statut: aheadofprint

Résumé

Magnesium sulfate (MgSO A retrospective matched-pair analysis from patients of a single center in Germany was performed without (group A) and with (group B) MgSO 196 patients fulfilled the inclusion criteria. After risk stratification, 48 patients were included in the final analysis (mean±SD age 54.2±8.1yrs, 30 f, 18 m) and were assigned to group A (n=24) or group B (n=24). CV occurred less frequently in group B (33%) than in A (46%). Likewise, DCI was present in 13% (group B) as compared to 42% (group A). After 12 months, 22 patients of group B had a favorable functional outcome (mRS 0 to 3) compared to 15 of group A. In this study, the incidence of CV and DCI was lower in patients receiving intravenous MgSO

Identifiants

pubmed: 38514031
pii: S1878-8750(24)00448-0
doi: 10.1016/j.wneu.2024.03.062
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

Auteurs

Julian Feulner (J)

Department of Neurosurgery, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany; Department of Neurosurgery, Klinikum Fürth, Jakob-Henle-Straße 1, 90766 Fürth, Germany.

Cornelia S Weidinger (CS)

Department of Anesthesiology, University Hospital Erlangen, Krankenhausstraße 12, 91054 Erlangen, Germany.

Arnd Dörfler (A)

Department of Neuroradiology, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

Torsten Birkholz (T)

Department of Anesthesiology, University Hospital Erlangen, Krankenhausstraße 12, 91054 Erlangen, Germany.

Michael Buchfelder (M)

Department of Neurosurgery, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

Björn Sommer (B)

Department of Neurosurgery, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany; Department of Neurosurgery, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany. Electronic address: bjoern.sommer@uk-augsburg.de.

Classifications MeSH