Dilation of ion selectivity filters in cation channels.
ATP-activated P2X receptor channels
Kv channels
TRP channels
ion selectivity
Journal
Trends in biochemical sciences
ISSN: 0968-0004
Titre abrégé: Trends Biochem Sci
Pays: England
ID NLM: 7610674
Informations de publication
Date de publication:
20 Mar 2024
20 Mar 2024
Historique:
received:
12
12
2023
revised:
19
02
2024
accepted:
23
02
2024
medline:
22
3
2024
pubmed:
22
3
2024
entrez:
21
3
2024
Statut:
aheadofprint
Résumé
Ion channels establish the voltage gradient across cellular membranes by providing aqueous pathways for ions to selectively diffuse down their concentration gradients. The selectivity of any given channel for its favored ions has conventionally been viewed as a stable property, and in many cation channels, it is determined by an ion-selectivity filter within the external end of the ion-permeation pathway. In several instances, including voltage-activated K
Identifiants
pubmed: 38514273
pii: S0968-0004(24)00049-5
doi: 10.1016/j.tibs.2024.02.004
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of interests No interests are declared.